US2005101619A1PendingUtilityA1

Anti-picornaviral compounds

Assignee: HARVARD COLLEGEPriority: Dec 11, 1997Filed: Dec 13, 2004Published: May 12, 2005
Est. expiryDec 11, 2017(expired)· nominal 20-yr term from priority
G01N 2333/105G01N 2333/085G01N 2500/00G01N 2333/095C12Q 1/70G01N 33/56983
45
PatentIndex Score
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Cited by
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Claims

Abstract

The present invention is broadly directed to methods of screening viral-binding compounds. In particular, the present invention provides cell-free assays to rapidly screen libraries of compounds for viral-capsid binding activity. Such compounds are useful for anti-viral treatments.

Claims

exact text as granted — not AI-modified
1 . A compound represented by the molecular formulas comprising: 
 a)                        wherein 
 i) R 1  is  
                     
  and 
 R 2  is selected from the group consisting of  
                     
 
 ii) R 1  is  
                     
  and 
 R 2  is  
                     
 
 iii) R 1  is  
                     
  and 
 R 2  is selected from the group consisting of  
 
     b)                        wherein 
 i) R 3  is  
                     
  and 
 R 4  is selected from the group consisting of  
                     
 
 ii) R 3  is  
                     R 4  is                          
 iii) R 3  is  
                     R 4  is selected from the group consisting of                          
     
     
     
         2 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         3 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         4 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         5 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         6 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         7 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         8 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         9 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         10 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         11 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         12 . The compound of  claim 1  represented by the molecular formula:  
       
         
           
           
               
               
           
         
       
     
     
         13 . The compound of  claim 1  represented by the molecular formula:

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