Antioxidant combination composition and use thereof

Abstract

An orally or parenterally administrable composition which comprises the following components: (a) L-carnitine inner salt or a pharmacologically acceptable salt thereof; (b) acetyl L-carnitine inner salt or a pharmacologically acceptable salt thereof; (c) α-lipoic acid; (d) coenzyme Q 10 ; (e) Vitamin E; and (f) selenomethionine, suitable for counteracting oxidative stress and use thereof are disclosed.

1 - 24 . (canceled)  
     
     
         25 . A therapeutic method for treating a disorder or disease associated with oxidative stress which comprises administering to a patient in need thereof an effective amount of a combination composition consisting essentially of: 
 (a) 20-110 mg L-carnitine inner salt or a pharmacologically acceptable salt thereof;    (b) 20-110 mg acetyl L-carnitine inner salt or a pharmacologically acceptable salt thereof;    (c) 70-130 mg α-lipoic acid;    (d) 90-110 mg coenzyme Q 10 ;    (e) 5-15 mg Vitamin E; and    (f) 40-60 μg selenomethionine.    
     
     
         26 . A therapeutic method for preventing a disorder or disease associated with oxidative stress which comprises administering to a patient in need thereof an effective amount of a combination composition consisting essentially of: 
 (a) 20-110 mg L-carnitine inner salt or a pharmacologically acceptable salt thereof;    (b) 20-110 mg acetyl L-carnitine inner salt or a pharmacologically acceptable salt thereof;    (c) 70-130 mg α-lipoic acid;    (d) 90-110 mg coenzyme Q 10 ;    (e) 5-15 mg Vitamin E; and    (f) 40-60 μg selenomethionine.