US2005142619A1PendingUtilityA1
Antibodies to mammalian langerhans cell antigen and their uses
Est. expirySep 25, 2018(expired)· nominal 20-yr term from priority
Inventors:Valerie Duvert-FrancesJean-Jacques PinJenny ValladeauValerie ClairSem SaelandSerge Lebecque
C07K 16/2851C07K 14/705
47
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Claims
Abstract
Purified mammalian DC cell surface protein, designated Langerin, nucleic acids encoding Langerin, and antibodies which specifically bind Langerin.
Claims
exact text as granted — not AI-modified1 . An isolated antibody which selectively binds a mammalian polypeptide, said polypeptide characterized by:
a) binds with selectively to DCGM4 monoclonal antibody; b) natural form of said polypeptide has a molecular weight by SDS PAGE of ˜40 kD; and c) expressed on the cell surface of Langerhans cells.
2 . The antibody of claim 1 which is a monoclonal antibody.
3 . A hybridoma that produces a monoclonal antibody of claim 2 .
4 . The hybridoma of claim 3 , which has ATCC Accession No. HB-12576.
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