US2005142619A1PendingUtilityA1

Antibodies to mammalian langerhans cell antigen and their uses

Assignee: SCHERING CORPPriority: Sep 25, 1998Filed: Jan 21, 2005Published: Jun 30, 2005
Est. expirySep 25, 2018(expired)· nominal 20-yr term from priority
C07K 16/2851C07K 14/705
47
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Claims

Abstract

Purified mammalian DC cell surface protein, designated Langerin, nucleic acids encoding Langerin, and antibodies which specifically bind Langerin.

Claims

exact text as granted — not AI-modified
1 . An isolated antibody which selectively binds a mammalian polypeptide, said polypeptide characterized by: 
 a) binds with selectively to DCGM4 monoclonal antibody;    b) natural form of said polypeptide has a molecular weight by SDS PAGE of ˜40 kD; and    c) expressed on the cell surface of Langerhans cells.    
     
     
         2 . The antibody of  claim 1  which is a monoclonal antibody.  
     
     
         3 . A hybridoma that produces a monoclonal antibody of  claim 2 .  
     
     
         4 . The hybridoma of  claim 3 , which has ATCC Accession No. HB-12576.  
     
     
         5 - 15 . (canceled)

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