US2005143289A1PendingUtilityA1

Botulinum toxin pharmaceutical composition

65
Assignee: ALLERGAN INCPriority: Feb 8, 2000Filed: Feb 25, 2005Published: Jun 30, 2005
Est. expiryFeb 8, 2020(expired)· nominal 20-yr term from priority
A61K 9/0019A61K 9/19A61K 47/36A61K 38/4893A61K 47/183A61P 21/00Y02A50/30
65
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Claims

Abstract

A botulinum toxin pharmaceutical formulation free of animal derived proteins, comprising a botulinum toxin and a recombinant albumin, suitable for therapeutic administration to a human patient, and methods for treating patients with various diseases and afflictions with the formulation.

Claims

exact text as granted — not AI-modified
1 - 19 . (canceled)  
     
     
         20 . A pharmaceutical composition comprising a botulinum toxin type A complex with a molecular weight of about 300 kD.  
     
     
         21 . A pharmaceutical composition comprising a botulinum toxin type A complex with a molecular weight of about 300 kD, wherein the pharmaceutical composition is substantially free of non-300 kD botulinum toxin type A complexes.  
     
     
         22 . The pharmaceutical composition of  claim 21 , wherein the pharmaceutical composition is substantially free of about 900 kD and about 500 kD botulinum toxin complexes.  
     
     
         23 . The pharmaceutical composition of  claim 22 , wherein the pharmaceutical composition is essentially free of about 900 kD and about 500 kD botulinum toxin complexes.  
     
     
         24 . The pharmaceutical composition of  claim 23 , wherein the pharmaceutical composition is entirely free of about 900 kD and about 500 kD botulinum toxin complexes.  
     
     
         25 . A pharmaceutical composition consisting essentially of botulinum toxin type A complex with a molecular weight of about 300 kD.  
     
     
         26 . A pharmaceutical composition consisting of a botulinum toxin type A complex with a molecular weight of about 300 kD.

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