Peptides and polypeptides derived from the submaxillary gland of the rat, corresponding polyclonal and monoclonal antibodies, corresponding hybridomas and uses of these products for diagnosis, for detection or therapeutic purposes

Abstract

The invention relates to peptides having the formula (I): X-His-Asn-Pro-Y wherein X is a rest Gln or pyro-Glu. Y is a group OH or a rest of basic aminoacid.

1 - 14 . (canceled)  
     
     
         15 . An isolated nucleic acid having the nucleotide sequence of nucleotides 1 to 510 of SEQ ID NO: 7, or a sequence hybridizing thereto, in a hybridization solution containing: 
 0.75 M sodium phosphate, pH 7.2,    7% sodium dodecylsulfate,    1 mM EDTA,    1% bovine serum albumin, and    sonicated salmon sperm DNA: 100 mg/ml, at 65° C.;    and after washing four times for 10 minutes at 65° C. with a solution containing:    40 mM sodium phosphate, pH 7.2,    1% sodium dodccylsulfate, and    1 mM EDTA.