US2005158316A1PendingUtilityA1
Antibody formulation
Est. expiryJun 13, 2017(expired)· nominal 20-yr term from priority
Inventors:Xanthe M. LamJames Q. OesweinBoonsri OngpipattanakulZahra ShahrokhSharon X. WangRobert P. WeissburgRita L. Wong
C07K 2317/54A61K 39/39591C07K 16/2845C07K 16/2896
49
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Claims
Abstract
A method of treating hemorrhagic shock with a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.8 to about 5.5, a surfactant and a polyol.
Claims
exact text as granted — not AI-modified1 . A method of treating a hemorrhagic shock in a mammal, comprising administering a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody that binds CD18, the antibody not subjected to prior lyophilization, an acetate buffer from about pH 4.8 to about 5.5, a surfactant and a polyol, wherein the formulation lacks a tonicifying amount of sodium chloride.
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