US2005176758A1PendingUtilityA1

Novel compounds and methods for synthesis and therapy

31
Priority: Feb 27, 1995Filed: May 24, 1996Published: Aug 11, 2005
Est. expiryFeb 27, 2015(expired)· nominal 20-yr term from priority
Y02P20/55A61P 31/16A61P 43/00A61P 31/04A61P 31/12C07D 309/28
31
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Claims

Abstract

Novel compounds are described. The compounds generally comprise an acidic group, a basic group, a substituted amino or N-acyl and a group having an optionally hydroxylated alkane moiety. Pharmaceutical compositions comprising the inhibitors of the invention are also described. Methods of inhibiting neuraminidase in samples suspected of containing neuraminidase are also described. Antigenic materials, polymers, antibodies, conjugates of the compounds of the invention with labels, and assay methods for detecting neuraminidase activity are also described.

Claims

exact text as granted — not AI-modified
1 - 21 . (canceled)  
     
     
         22 : A compound having the formula:  
       
         
           
           
               
               
           
         
       
       wherein: 
 R 1  is H or C 1 -C 8  alkyl;  
 R 2  is H or CH 3 OCH 2 —; and  
 X is H or F;  
 and the salts, solvates, and enantiomers thereof.  
 
     
     
         23 : The compound of  claim 22  having formula 345:  
       
         
           
           
               
               
           
         
       
     
     
         24 : The compound of  claim 22  having formula 500:

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