Use of osteopontin in dental formulations

Abstract

Use of osteopontin for reducing plaque bacterial growth on tooth enamel and dental formulations containing osteopontin.

1 . Use of osteopontin for reducing or preventing plaque bacterial growth on tooth enamel.  
     
     
         2 . Use of osteopontin according to  claim 1  for reducing or preventing dental caries.  
     
     
         3 . Use of osteopontin according to  claim 1  for reducing or preventing calculus dentalis.  
     
     
         4 . Use of osteopontin according to  claim 1  for reducing or preventing periodontal disease.  
     
     
         5 . Use of osteopontin according to  claim 1  for reducing or preventing demineralization of teeth.  
     
     
         6 . A dental formulation containing osteopontin.  
     
     
         7 . A dental formulation according to  claim 6  in the form of a toothpaste, toothpowder, tooth gel, dental mouthwash, mouth spray or chewing gum.  
     
     
         8 . A dental formulation according to  claim 7  comprising about 5 mg osteopontin to about 1500 mg osteopontin per kg formulation.  
     
     
         9 . A dental formulation according to  claim 8  comprising about 100 mg osteopontin to about 1000 mg osteopontin per kg formulation.  
     
     
         10 . A dental formulation according to  claim 9  comprising about 200 mg osteopontin to about 500 mg osteopontin per kg formulation.  
     
     
         11 . A dental formulation according to  claim 10  comprising about 350 mg osteopontin per kg formulation.  
     
     
         12 . Use of osteopontin for the manufacturing of a pharmaceutical composition for treating or preventing dental caries, calculus dentalis or periodontal disease.  
     
     
         13 . A method for preventing or inhibiting plaque bacterial growth on tooth enamel by administration in the mouth of an effective amount of osteopontin.  
     
     
         14 . Method of treatment or preventing of dental caries, calculus dentalis or periodontal disease by oral administration of an effective amount of osteopontin to a patient in need of such treatment.