US2005214322A1PendingUtilityA1

Vaccines containing a saponin and a sterol

Assignee: SMITHKLINE BEECHAM BIOLOGPriority: Apr 25, 1995Filed: Oct 18, 2004Published: Sep 29, 2005
Est. expiryApr 25, 2015(expired)· nominal 20-yr term from priority
A61K 2039/55577A61K 39/292C12N 2740/13034A61K 2039/55505A61K 39/39A61K 39/12A61K 39/245A61K 2039/55572C12N 2710/16634C12N 2730/10134A61K 39/015A61K 2039/55555A61K 2039/57
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Claims

Abstract

The invention relates to a vaccine composition comprising an antigen, an immunologically active saponin fraction and a sterol.

Claims

exact text as granted — not AI-modified
1 .- 12 . (canceled)  
     
     
         13 . An adjuvant composition comprising a sterol and a substantially pure preparation of QS21, characterized in that the adjuvant composition is in the form of an ISCOM.  
     
     
         14 . An adjuvant composition according to claim  1 , wherein the QS21 is at least 90% pure.  
     
     
         15 . An adjuvant composition according to claim  1 , wherein the QS21 is at least 95% pure.  
     
     
         16 . An adjuvant composition according to claim  1 , wherein the QS21 is at least 98% pure.

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