Pressure sore treatment

Abstract

Methods for treating a pressure sore or for preventing development of a pressure sore by local administration of a Clostridial toxin, such as a botulinum neurotoxin, to a pressure sore or to a pressure point, or to the vicinity thereof.

1 . A method for treating a pressure sore, the method comprising the step of locally administering a therapeutically effective amount of a  botulinum  toxin to or to the vicinity of a pressure sore of a patient without substantially paralyzing a muscle, thereby treating a pressure sore.  
   
   
       2 . The method of  claim 1 , wherein the  botulinum  toxin is selected from the group consisting of  botulinum  toxin types A, B, C, D, E, F and G.  
   
   
       3 . The method of  claim 1 , wherein the  botulinum  toxin is a  botulinum  toxin type A.  
   
   
       4 . The method of  claim 1 , wherein the  botulinum  toxin is administered in an amount of between about 1 unit and about 3,000 units.  
   
   
       5 . The method of  claim 1 , wherein the administration is by topical or subcutaneous administration of the  botulinum  toxin.  
   
   
       6 . A method for treating a pressure sore, the method comprising the step of locally administering a therapeutically effective amount of a  botulinum  toxin to a pressure sore or to the vicinity of a pressure sore of a patient without substantially paralyzing a muscle, thereby treating the pressure sore by facilitating healing of the pressure sore.  
   
   
       7 . A method for preventing development of a pressure sore, the method comprising the step of locally administering a therapeutically effective amount of a  botulinum  toxin to or to the vicinity of a pressure point of a patient without substantially paralyzing a muscle, thereby preventing development of a pressure sore.  
   
   
       8 . The method of  claim 7 , wherein the  botulinum  toxin is selected from the group consisting of  botulinum  toxin types A, B, C1, D, E, F and G.  
   
   
       9 . The method of  claim 7 , wherein the  botulinum  toxin is a  botulinum  toxin type A.  
   
   
       10 . The method of  claim 7 , wherein the  botulinum  toxin is administered in an amount of between about 5 units and about 25,000 units.  
   
   
       11 . The method of  claim 7 , wherein the administration is by topical or subcutaneous administration of the  botulinum  toxin.  
   
   
       12 . A method for preventing development of a pressure sore, the method comprising the step of locally administering a therapeutically effective amount of a  botulinum  toxin to or to the vicinity of a pressure point of a patient without substantially paralyzing a muscle, thereby preventing development of a pressure sore.  
   
   
       13 . A method for treating a pressure sore, the method comprises the step of locally administering a therapeutically effective amount of a  botulinum  toxin type A to a pressure sore without substantially paralyzing a muscle, thereby treating the pressure sore.  
   
   
       14 . The method of  claim 1 , wherein the pressure sore is a result of immobility of the patient.