Topical anti-cancer compositions and methods of use thereof

Abstract

Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors.

1 - 49 . (canceled)  
     
     
         50 . A method for preventing and reducing the risk of skin cancer comprising topical application of at least one composition comprising a non-denatured, soy product in an amount of from about 0.01-99% by weight in a carrier.  
     
     
         51 . The method of  claim 50 , wherein said composition is applied at least once daily on a continuous basis.  
     
     
         52 . The method of  claim 50 , wherein said composition is applied at least twice daily for at least eight weeks and at least once daily on a continuous basis thereafter.  
     
     
         53 . The method of  claim 50 , wherein a first composition comprising non-denatured, soy product in an amount of 0.05-80% by weight is applied for at least about four to about ten weeks followed by topical application of a second composition comprising non-denatured, soy product in an amount of 0.01-20% by weight on a daily basis thereafter.  
     
     
         54 . The method of  claim 50 , wherein said composition further comprises a cosmetically acceptable vehicle.  
     
     
         55 . The method of  claim 50 , wherein said composition further comprises at least one compound selected from the group consisting of anti-oxidants, sunscreens, moisturizers, bleaching agents, depigmentation agents, darkening agents, surfactants, foaming agents, conditioners, humectants, fragrances, anti-aging agents, anti-inflammatory agents, and anti-cancer agents.  
     
     
         56 . The method of  claim 55 , wherein said composition further comprises at least one anti-inflammatory agent.  
     
     
         57 . The method of  claim 55 , wherein said composition further comprises at least one anti-cancer agent.  
     
     
         58 . The method of  claim 55 , wherein said composition further comprises at least one anti-oxidant.  
     
     
         59 . The method of  claim 55 , wherein said composition further comprises at least one sunscreen.  
     
     
         60 . The method of  claim 50 , wherein said non-denatured, soy product is selected from the group consisting of soymilk, soybean powder, soymilk powder, and Kunitz-type soybean trypsin inhibitor.  
     
     
         61 . The method of  claim 60 , wherein said non-denatured, soy product is soymilk.  
     
     
         62 . The method of  claim 60 , wherein said non-denatured, soy product is soybean powder or soymilk powder.  
     
     
         63 . The method of  claim 60 , wherein said non-denatured, soy product is Kunitz-type soybean trypsin inhibitor.  
     
     
         64 . The method of  claim 61 , wherein said soymilk is in an amount of 0.05% to 80%, said composition further comprising from about 0.1% to about 20% emulsifier and a preservative in an effective amount.  
     
     
         65 . The method of  claim 64 , wherein said composition further comprises at least one compound selected from the group consisting of anti-oxidants, sunscreens, moisturizers, bleaching agents, depigmentation agents, darkening agents, surfactants, foaming agents, conditioners, humectants, fragrances, anti-aging agents, anti-inflammatory agents, and anti-cancer agents.  
     
     
         66 . The method of  claim 65 , wherein said composition further comprises at least one anti-oxidant.  
     
     
         67 . The method of  claim 65 , wherein said compositions further comprises at least one anti-cancer agent.  
     
     
         68 . The method of  claim 65 , wherein said composition further comprises at least one sunscreen.  
     
     
         69 . The method of  claim 65 , wherein said composition further comprises at least one anti-inflammatory agent.  
     
     
         70 . The method of  claim 62 , wherein said soybean powder or soymilk powder is in an amount of 0.05% to 80%, said composition further comprising from about 0.1% to about 20% emulsifier and a preservative in an effective amount.  
     
     
         71 . The method of  claim 70 , wherein said composition further comprises at least one compound selected from the group consisting of anti-oxidants, sunscreens, moisturizers, bleaching agents, depigmentation agents, darkening agents, surfactants, foaming agents, conditioners, humectants, fragrances, anti-aging agents, anti-inflammatory agents, and anti-cancer agents.  
     
     
         72 . The method of  claim 71 , wherein said composition further comprises at least one anti-oxidant.  
     
     
         73 . The method of  claim 71 , wherein said compositions further comprises at least one anti-cancer agent.  
     
     
         74 . The method of  claim 71 , wherein said composition further comprises at least one sunscreen.  
     
     
         75 . The method of  claim 71 , wherein said composition further comprises at least one anti-inflammatory agent.  
     
     
         76 . The method of  claim 63 , wherein said Kunitz-type soybean trypsin inhibitor is in an amount of from about 0.01 to about 10%, said composition further comprising from about 0.1 to about 20% emulsifier and a preservative in an effective amount.  
     
     
         77 . The method of  claim 76 , wherein said composition further comprises at least one compound selected from the group consisting of anti-oxidants, sunscreens, moisturizers, bleaching agents, depigmentation agents, darkening agents, surfactants, foaming agents, conditioners, humectants, fragrances, anti-aging agents, anti-inflammatory agents, and anti-cancer agents.  
     
     
         78 . The method of  claim 77 , wherein said composition further comprises at least one anti-oxidant.  
     
     
         79 . The method of  claim 77 , wherein said compositions further comprises at least one anti-cancer agent.  
     
     
         80 . The method of  claim 77 , wherein said composition further comprises at least one sunscreen.  
     
     
         81 . The method of  claim 77 , wherein said composition further comprises at least one anti-inflammatory agent.