Hydrogen peroxide-based skin disinfectant

Abstract

A skin disinfectant in ready-to-use concentrated liquid or dry powdered form. Ready-to-use liquid forms have a pH of from about 2 to about 6 and include: (a) hydrogen peroxide in a concentration of from about 0.01 to about 4% w/w of the solution; (b) at least one surfactant chosen from imidazoline derivatives, alkyl betaines, alkyl amidopropyl betaine amides, alkyl amidopropyl betaines, alkylsulfo betaines, amine oxides and derivatives thereof in a concentration of from about 0.01 to about 15% w/w of the solution; (c) at least one hydrogen peroxide stabilizer in a concentration of from about 0.01 to about 4% w/w of the solution; (d) at least one member chosen from cyclic carboxylic acids and salts thereof in a concentration of from about 0.01 to about 4% w/w of the solution; and (e) at least one skin conditioning agent in a concentration of from about 0.01 to about 10% w/w of the solution.

1 . An aqueous skin disinfecting solution having a pH of from about 2 to about 6 and comprising: 
 (a) hydrogen peroxide in a concentration of from about 0.01 to about 4% w/w of the solution;    (b) at least one surfactant chosen from imidazoline derivatives, alkyl betaines, alkyl amidopropyl betaine amides, alkyl amidopropyl betaines, alkylsulfo betaines, amine oxides and derivatives thereof in a concentration of from about 0.01 to about 15% w/w of the solution;    (c) at least one hydrogen peroxide stabilizer in a concentration of from about 0.01 to about 4% w/w of the solution;    (d) at least one member chosen from cyclic carboxylic acids and salts thereof in a concentration of from about 0.01 to about 4% w/w of the solution; and    (e) at least one skin conditioning agent in a concentration of from about 0.01 to about 10% w/w of the solution.    
     
     
         2 . The solution of  claim 1 , wherein the imidazoline derivatives are chosen from alkylamphocarboxylates and alkyliminocarboxylates.  
     
     
         3 . The solution of  claim 1 , wherein the hydrogen peroxide stabilizer is chosen from phosphoric acid, phosphonic acids having 1 to 5 phosphonic acid groups, ethylenediaminetetraacetic acid (EDTA), diethylenetriaminepentaacetic acid (DTPA), N-(hydroxyethyl)-ethylenediaminetriacetic acid (HEDTA), nitrilotriacetic acid (NTA), 2-hydroxyethyliminodiacetic acid (HEIDA), benzoic acid, aminobenzoic acid, citric acid, iminodisuccinic acid, polyaspartic acid, and salts thereof.  
     
     
         4 . The solution of  claim 3 , wherein the hydrogen peroxide stabilizer is chosen from sodium tripolyphosphate, 1-hydroxyethylidene-1,1,-diphosphonic acid, amino tri(methylene phosphonic acid), diethylenetriaminepenta(methylene phosphonic acid), 2-hydroxy ethylimino bis(methylene phosphonic acid), and ethylene diamine tetra(methylene phosphonic acid).  
     
     
         5 . The solution of  claim 1 , wherein the carboxylic acid is chosen from furan carboxylic acid, benzoic acid and salicylic acid.  
     
     
         6 . The solution of  claim 5 , comprising 2-furan carboxylic acid.  
     
     
         7 . The solution of  claim 1 , wherein the skin conditioning agent is chosen from glycerides, sorbitol, castor oil, allantoin, cationic polymers, lanolin and its derivatives and cetyl alcohol.  
     
     
         8 . The solution of  claim 1 , comprising at least one buffer in a concentration of from about 0.01 to about 5% w/w of the solution.  
     
     
         9 . The solution of  claim 8 , wherein the buffer is chosen from citric acid, lactic acid, glycolic acid, phosphoric acid, malic acid, succinic acid and tartaric acid.  
     
     
         10 . The solution of  claim 1 , comprising at least one hydrogen peroxide compatible surfactant in a concentration of from about 0.01 to about 10% w/w of the solution.  
     
     
         11 . The solution of  claim 1 , comprising at least one C1 to C8 alcohol chosen from benzyl alcohol, ethanol, n-butanol, isopropanol, glycols in a concentration of from about 0.01 to about 10% w/w of solution.  
     
     
         12 . The solution of  claim 1 , comprising at least one thickening agent compatible with hydrogen peroxide in a concentration of from about 0.01 to about 5% w/w of the solution.  
     
     
         13 . The solution of  claim 12 , wherein the thickening agent is chosen from polyacrylic acid polymers, polysaccharides, and cellulose based polymers.  
     
     
         14 . The solution of  claim 1 , comprising at least one member chosen from dyes and fragrances in a concentration of from about 0.001 to about 0.5% w/w of the solution.  
     
     
         15 . The solution of  claim 1 , wherein the pH is from about 2.5 to about 5.  
     
     
         16 . The solution of  claim 1 , wherein the hydrogen peroxide is present in a concentration of from about 0.25 to about 3% w/w of the solution.  
     
     
         17 . The solution of  claim 1 , further comprising at least one member chosen from monocarboxylic acids, polycarboxylic acids, and mixtures thereof in a concentration of from about 0.01 to about 3% w/w of the solution.  
     
     
         18 . An aqueous skin disinfecting solution having a pH of from about 2.5 to about 5 and comprising: 
 (a) hydrogen peroxide in a concentration of from about 1 to about 3% w/w of the solution;    (b) at least one surfactant chosen from alkyl betaines, alkyl amidopropyl betaines, alkyl amidopropyl betaine amides, alkylsulfo betaines, alkyl amphocarboxylates, alkyliminocarboxylates, amine oxides and derivatives thereof in a concentration of from about 1 to about 5% w/w of the solution;    (c) at least one hydrogen peroxide stabilizer in a concentration of from about 0.01 to about 2% w/w of the solution;    (d) at least one member chosen from cyclic carboxylic acids and salts thereof in a concentration of from about 0.05 to about 1 % w/w of the solution; and    (e) at least one skin conditioning agent in a concentration of from about 0.5 to about 4% w/w of the solution.    
     
     
         19 . A concentrated skin disinfectant solution, which can be diluted with water to form the solution of  claim 1 .  
     
     
         20 . A dry powdered formulation, which can be dissolved in water to form the solution of  claim 1.