Dosage form for hormonal contraception

Abstract

The present invention relates to a dosage form for hormonal contraception containing a given number of hormone-containing daily units and a given number of hormone-free daily units for daily, oral administration, characterised in that the hormone-containing daily units each contain at most the minimum effective daily amount of folic acid for women and the hormone-free daily units contain at least a multiple of this amount up to the maximum permissible amount of folic acid for women.

1 . A dosage form for hormonal contraception containing a given number of hormone-containing daily units and a given number of hormone-free daily units for uninterrupted daily oral administration to women, characterised in that the hormone-containing daily units contain folic acid in a daily amount of at most 200 μg and the hormone-free daily units in each case contain folic acid in a daily amount of >200 μg up to the maximum permissible amount for women of folic acid:  
     
     
         2 . A dosage form according to  claim 1 , characterised in that the hormone-containing daily units each contain 5 to 200 μg of folic acid.  
     
     
         3 . A dosage form according to  claim 1 , characterised in that the hormone-containing daily units do not contain any folic acid.  
     
     
         4 . A dosage form according to  claim 1 , characterised in that the hormone-containing daily units contain folic acid in an amount up to the minimum effective daily amount for women.  
     
     
         5 . A dosage form according to  claim 1 , characterised in that the hormone-free daily units each contain more than 200 μg and up to 5 mg.  
     
     
         6 . A dosage form according to  claim 1 , characterised in that the hormone-containing daily units each contain the same amount of folic acid and the hormone-free daily units likewise each contain the same amount of folic acid.  
     
     
         7 . A dosage form according to  claim 1 , characterised in that it comprises at least 21 hormone-containing daily units and 7 to 3 hormone-free daily units.  
     
     
         8 . A dosage form according to  claim 7 , characterised in that its maximum number of hormone-containing daily units is sufficient for administration for several years, preferably for 2 years, particularly preferably for 1 year, and the number of hormone-free daily units corresponds to 7 to 3 days.  
     
     
         9 . A dosage form according to  claim 7 , characterised in that it comprises up to 730, preferably up to 365, hormone-containing daily units and 7 to 3 hormone-free daily units.  
     
     
         10 . A dosage form according to  claim 7 , characterised in that it comprises 21 to 25 hormone-containing daily units and 7 to 3 hormone-free daily units.  
     
     
         11 . A dosage form according to  claim 7 , characterised in that it comprises 42 to 52 hormone-containing daily units and 7 to 3 hormone-free daily units.  
     
     
         12 . A dosage form according to  claim 7 , characterised in that it comprises 77 to 193 hormone-containing daily units and 7 to 3 hormone-free daily units.  
     
     
         13 . A dosage form according to  claim 1 , characterised in that the hormone-containing daily units each contain at least one contraceptively active hormone component, preferably a combination of hormone components, particularly preferably a combination of an oestrogen and a gestagen.  
     
     
         14 . A dosage form according to  claim 1 , characterised in that the number of hormone-containing daily units corresponds to a monophasic contraceptive.  
     
     
         15 . A kit containing at least one dosage form for hormonal contraception according to  claim 1 .  
     
     
         16 . A kit according to  claim 15 , characterised in that it contains a plurality of dosage forms according to  claim 1  any one of  1 .