Medical compositions containing an ionic salt, kits, and methods

Abstract

A hardenable medical composition (preferably, dental composition) that includes an ionic redox polymerization system and at least one secondary ionic salt that includes a cation selected from the group consisting of a Group I ion, a Group II ion, an ammonium ion of the formula NR 4 + wherein each R is H or a (C1-C4)alkyl group, and mixtures thereof.

1 . A hardenable dental composition comprising: 
 a hardenable resin system comprising an ethylenically unsaturated component;    water;    an ionic redox polymerization system comprising an ionic oxidizing agent, a reducing agent comprising a urea or thiourea functional group; and    a secondary ionic salt comprising a cation selected from the group consisting of a Group I ion, a Group II ion, an ammonium ion of the formula NR 4   +  wherein each R is H or a (C1-C4)alkyl group, and mixtures thereof.    
   
   
       2 . The hardenable dental composition of  claim 2  wherein the hardenable resin system further comprises an acid-functional component.  
   
   
       3 . The hardenable dental composition of  claim 3  further comprising an acid-reactive filler.  
   
   
       4 . The hardenable dental composition of  claim 2  which is a dental sealant, dental adhesive, dental cement, dental restorative, or a dental prostheses.  
   
   
       5 . The hardenable dental composition of  claim 2  wherein the reducing agent is polymerizable or nonpolymerizable.  
   
   
       6 . A kit for forming a dental composition, the kit comprising one or more containers whose contents collectively comprise: 
 a hardenable resin system comprising an ethylenically unsaturated component and an acid-functional component;    water;    an acid-reactive filler;    an ionic redox polymerization system comprising an ionic oxidizing agent; and    a secondary ionic salt comprising a cation selected from the group consisting of a Group I ion, a Group II ion, an ammonium ion of the formula NR 4   +  wherein each R is H or a (C1-C4)alkyl group, and mixtures thereof.    
   
   
       7 . The kit of  claim 6  wherein the dental composition is a dental sealant, dental adhesive, dental cement, dental restorative, or a dental prostheses.  
   
   
       8 . A kit for forming a dental composition, the kit comprising one or more containers whose contents collectively comprise: 
 a hardenable resin system comprising an ethylenically unsaturated component;    water;    an ionic redox polymerization system comprising an ionic oxidizing agent, a reducing agent comprising a urea or thiourea functional group; and    a secondary ionic salt comprising a cation selected from the group consisting of a Group I ion, a Group II ion, an ammonium ion of the formula NR 4   +  wherein each R is H or a (C1-C4)alkyl group, and mixtures thereof.    
   
   
       9 . The kit of  claim 8  wherein the dental composition is a dental sealant, dental adhesive, dental cement, dental restorative, or a dental prostheses.  
   
   
       10 . A method of cementing a dental article to a tooth or bone, the method comprising: 
 providing a dental article;    providing a hardenable composition comprising: 
 a hardenable resin system comprising an ethylenically unsaturated component;  
 water;  
 an ionic redox polymerization system comprising an ionic oxidizing agent, a reducing agent comprising a urea or thiourea functional group; and  
 a secondary ionic salt comprising a cation selected from the group consisting of a Group I ion, a Group II ion, an ammonium ion of the formula NR 4   +  wherein each R is H or a (C1-C4)alkyl group, and mixtures thereof; and  
 cementing the dental article to the tooth or bone using the hardenable composition.