US2006035263A1PendingUtilityA1

DRG11-responsive (DRAGON) gene family

Assignee: GEN HOSPITAL CORPPriority: Apr 18, 2002Filed: Sep 19, 2005Published: Feb 16, 2006

Est. expiryApr 18, 2022(expired)· nominal 20-yr term from priority

Inventors:Clifford J. Woolf Tarek A. Samad

A61P 9/00A61P 37/00A61P 43/00A61P 35/00A61P 25/00C07K 2317/92C07K 14/47C12Q 2600/158C07K 16/18A01K 2217/05C12Q 2600/112C07K 14/461A61K 38/00A61P 17/00C12Q 2600/156A61P 21/00A61P 19/00A61K 38/179A01K 2217/075G01N 2333/71C07K 14/43509C12Q 1/6886G01N 33/5758

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Claims

Abstract

This invention features methods and compositions useful for treating and diagnosing diseases of the nervous system, retina, skin, muscle, joint, and cartilage using a Dragon family protein. Protein and nucleic acid sequences of human, murine, zebrafish, and C. elegans Dragon family members are also disclosed.

Claims

exact text as granted — not AI-modified

1 . A method for diagnosing a patient as having a Dragon-related condition comprising assessing a Dragon gene in said patient, wherein said Dragon gene comprises a mutation resulting in altered Dragon biological activity.  
     
     
         2 . The method of  claim 1 , wherein said Dragon gene is DRAGON.  
     
     
         3 . The method of  claim 1 , wherein said assessing comprises the polymerase chain reaction.  
     
     
         4 . The method of  claim 1 , wherein said assessing comprises restriction fragment length polymorphism (RFLP) analysis.

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