System and methods for processing analyte sensor data

Abstract

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

1 . a method for displaying substantially continuous analyte sensor data, the method comprising: 
 receiving a data stream from an analyte sensor, the data stream comprising a plurality of sensor data points;    processing the plurality of sensor data points to obtain calibrated continuous sensor data; and    displaying the calibrated continuous sensor data as a graphical representation.    
     
     
         2 . the method of  claim 1 , wherein the processing step comprises prospectively calibrating the plurality of sensor data points.  
     
     
         3 . the method of  claim 1 , wherein the processing step comprises substantially continuously calibrating the sensor data points to provide substantially continuous real-time analyte value estimates.  
     
     
         4 . the method of  claim 1 , wherein the graphical representation is displayed on a substantially pager-sized receiver device.  
     
     
         5 . the method of  claim 1 , wherein the graphical representation is displayed on a receiver device configured to be worn by a person.  
     
     
         6 . the method of  claim 1 , wherein the graphical representation is displayed on a liquid crystal display screen.  
     
     
         7 . the method of  claim 1 , wherein the displaying step comprises displaying historical trend data on a user interface.  
     
     
         8 . the method of  claim 7 , wherein the historical trend data comprises real-time data for a predetermined time period.  
     
     
         9 . the method of  claim 7 , wherein the displaying step comprises displaying calibrated continuous sensor data selected from the group consisting of approximately 1 hour of the calibrated continuous sensor data, approximately 3 hours of the calibrated continuous sensor data, approximately 9 hours of the calibrated continuous sensor data, and combinations thereof.  
     
     
         10 . the method of  claim 7 , wherein the displaying step comprises selectively displaying calibrated continuous sensor data selected from the group consisting of approximately 1 hour of the calibrated continuous sensor data, approximately 3 hours of the calibrated continuous sensor data, approximately 9 hours of the calibrated continuous sensor data.  
     
     
         11 . a system for displaying continuous analyte sensor data, comprising: 
 a sensor data module operatively connected to a continuous analyte sensor that receives a data stream comprising a plurality of time spaced sensor data points from the analyte sensor;    a processor module operatively connected to the sensor data module that calibrates the plurality of time spaced sensor data points to obtain calibrated continuous sensor data; and    an interface control module operatively connected to the processor module and configured to display a graphical representation of the calibrated continuous sensor data.    
     
     
         12 . the system of  claim 11 , wherein the processor module is configured to prospectively calibrate the plurality of time spaced sensor data points.  
     
     
         13 . the system of  claim 11 , wherein the processor module is configured to substantially continuously calibrate the sensor data points to provide substantially continuous real-time sensor data.  
     
     
         14 . the system of  claim 11 , wherein the system comprises a substantially pager-sized receiver device and wherein the graphical representation is displayed thereon.  
     
     
         15 . the system of  claim 11 , wherein the system comprises a receiver device configured to be worn by a person and wherein the graphical representation is displayed on the receiver device.  
     
     
         16 . the system of  claim 11 , wherein the system comprises a liquid crystal display screen and wherein the graphical representation is displayed thereon.  
     
     
         17 . the system of  claim 11 , wherein the graphical representation comprises historical trend data displayed on a user interface.  
     
     
         18 . the system of  claim 17 , wherein the historical trend data comprises real-time data for a predetermined time period.  
     
     
         19 . the system of  claim 17 , wherein the historical trend data is selected from the group consisting of approximately 1 hour of the calibrated continuous sensor data, approximately 3-hours of the calibrated continuous sensor data, approximately 9 hours of the calibrated continuous sensor data, and combinations thereof.  
     
     
         20 . the system of  claim 19 , wherein the user interface is configured to selectively display historical trend data selected from the group consisting of approximately 1-hour of the calibrated continuous sensor data, approximately 3 hours of the calibrated continuous sensor data, and approximately 9 hours of the calibrated continuous sensor data.