Process for the production of optically active 3-phenylisoserine

Abstract

The invention relates to a process for preparation of (R, R)-3-phenylisoserine and its derivates.

1 - 8 . (canceled)  
     
     
         9 . A process for the production of 3-phenylisoserine or a salt or a 1-4C-alkyl ester thereof, which comprises 
 a. reacting a 3-phenylglycidic acid salt with ammonia,    b. obtaining a 3-phenylisoserine salt, and    c. optionally converting the 3-phenylisoserine salt into 3-phenylisoserine or into 3-phenylisoserine 1-4C-alkyl ester.    
     
     
         10 . The process according to  claim 9 , wherein the 3-phenylglycidic acid salt is the sodium salt.  
     
     
         11 . The process according to  claim 9 , wherein the reaction with ammonia is carried out in a protic solvent, with an ammonia concentration of about 15 to 33% and at a temperature between 25 and 75° C.