US2006051375A1PendingUtilityA1

Rabbit skin comprising biological active substances and its use

48
Individually held — no corporate assignee on recordPriority: Oct 31, 2002Filed: Oct 30, 2003Published: Mar 9, 2006
Est. expiryOct 31, 2022(expired)· nominal 20-yr term from priority
Inventors:Wing Cheung
A61P 35/02A61P 37/08A61P 25/04A61P 25/20A61P 29/00A61K 2039/54A61K 39/285A61K 35/12A61K 35/36A23J 1/10A61K 39/12A61P 17/02
48
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Claims

Abstract

A rabbit skin containing biologically active substances is obtained by the process including vaccinating rabbit skin tissues with vaccinia virus, feeding a rabbit vaccinated with vaccinia virus, killing the rabbit when its skin tissues are sufficiently inflamed, and skinning the rabbit. The rabbit skin of the present invention can be used for preparing drugs and health foods.

Claims

exact text as granted — not AI-modified
1 . A rabbit skin containing biologically active substances, said skin is obtained by the following process comprising: vaccinating rabbit skin tissues with vaccinia virus, feeding rabbit vaccinated with vaccinia virus, killing the rabbit when its skin tissues is sufficiently inflamed, and skinning the rabbit.  
   
   
       2 . The rabbit skin according to  claim 1 , wherein the said vaccinia virus is vaccinia virus Lister strain.  
   
   
       3 . The rabbit skin according to  claim 1 , wherein the said vaccinia virus is vaccinia virus Ikeda strain.  
   
   
       4 . The rabbit skin according to  claim 1 , wherein the said vaccinia virus is vaccinia virus Dairen strain.  
   
   
       5 . The rabbit skin according to  claim 1 , wherein the said vaccinia virus is vaccinia virus EM-63 strain.  
   
   
       6 . The rabbit skin according to  claim 1 , wherein the said vaccinating rabbit skin tissues with vaccinia virus is effected by injecting subcutaneously 0.1˜0.4 ml solution containing 10 6 ˜10 9  viruses/ml each site, 100 to 250 sites per rabbit weighing 1.5˜3 Kg.  
   
   
       7 . The rabbit skin according to  claim 1 , wherein the said rabbit is a Japanese white rabbit.  
   
   
       8 . The rabbit skin according to  claim 1 , wherein the said rabbit is a New Zealand white rabbit.  
   
   
       9 . The rabbit skin according to  claim 1 , wherein the said rabbit is a Chinese rabbit.  
   
   
       10 . The rabbit skin according to  claim 1 , wherein the said rabbit is a Blue-violet rabbit.  
   
   
       11 . The rabbit skin according to  claim 1 , wherein the said killing of the rabbit when its skin tissues are sufficiently inflamed is effected when the rabbit skin inflammatory tissue shows visible blains accompanying with changing colour from redness to mauveness and becomes thick, and its subcuticle and hip become swollen.  
   
   
       12 . The rabbit skin according to  claim 1 , which possesses 0.5 iu/g SART activity or more.  
   
   
       13 . The rabbit skin according to  claim 1 , which possesses kallikrein-protease inhibition activity.  
   
   
       14 . Use of the rabbit skin according to  claim 1 , characterized in that the rabbit skin is used for preparing at least one drug.  
   
   
       15 . Use of the rabbit skin according to  claim 1 , characterized in that the rabbit skin is used for preparing health food.

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