Composition for accelerating secretion of estrogen and regenerating tissue cells of female sexual organs

Abstract

The present invention relates to a composition for accelerating secretion of estrogen and regenerating tissue cells of female sexual organs, more particularly; to a composition for accelerating secretion of estrogen and regenerating tissue cells of female sexual organs in postmenopausal women comprising one or more of Platycodi Radix and Cynanchum wilfordii extract and/or Phlomis umbrosa extract. The present invention provides a composition, a pharmaceutical composition and a food composition capable of replacing estrogen, which comprise one or more selected from the group consisting of Platycodi Radix extract and Cynanchum wilfordii extract and/or Phlomis umbrosa extract. The composition of this invention comprised of the extracts of natural source shows little or no adverse effects such as cancer occurrence compared with estrogen-replacing agent used for conventional hormone replacement therapy; in addition, it has excellent effect on the regeneration and proliferation of tissue cells of female sexual organs, so that it is applicable to treatment of various disorders and diseases developed in postmenopausal women who are deficient in estrogen. Moreover, the composition of this invention has little impurities and high amount of active ingredients.

1 . A composition for accelerating estrogen secretion, which comprises as active ingredient one or more selected from the group consisting of  Platycodi Radix  extract and  Cynanchum wilfordii  extract.  
     
     
         2 . A pharmaceutical composition for treating or preventing a disorder associated with menopause, which comprises a pharmaceutically effective amount of one or more selected from the group consisting of  Platycodi Radix  extract and  Cynanchum wilfordii  extract; and a pharmaceutical acceptable carrier.  
     
     
         3 . A food composition for treating or preventing a disorder associated with menopause, which comprises as active ingredient one or more selected from the group consisting of  Platycodi Radix  extract and  Cynanchum wilfordii  extract, wherein the extract induces estrogen secretion.  
     
     
         4 . The composition according to any one of  claims 1  to  3 , which further comprises  Phlomis umbrosa  extract as active ingredient.  
     
     
         5 . The composition according to any one of  claims 1  to  3 , which regenerates or proliferates tissue cells of female sexual organ.  
     
     
         6 . The composition according to any one of  claims 1  to  3 , wherein the amount of the extract is 20-80% by weight of the total amount of the composition.  
     
     
         7 . The composition according to any one of  claims 1  to  3 , which further comprises one or more ingredients selected from the group consisting of calcium, arginin and lysine.  
     
     
         8 . The composition according to any one of  claims 1  to  3 , wherein the extract is an active fraction prepared in a process which comprises treating  Platycodi Radix  and  Cynanchum wilfordii  with hot water for obtaining an extract; and filtering the extract by means of ultrafiltration membrane with a molecular weight cut off of 50,000-100,000.