Therapeutic treatments using the direct application of antimicrobial metal compositions

Abstract

Therapeutic treatments using the direct application of selected structures of antimicrobial metals in free-standing powder form, solution form and/or suspension form in therapeutically effective amounts. The selected structures of antimicrobial metals serve as an antimicrobial agent, an anti-inflammatory agent, an immuno modulator agent, an enzyme modulator agent, and/or an anti-tumor agent, for human and/or animal use.

1 . A method for treating tissue, comprising: 
 forming a free-standing powder comprising at least one antimicrobial nanocrystalline metal with atomic disorder; and    injecting the free-standing powder in therapeutically effective amounts to the tissue which is to be treated.    
     
     
         2 - 22 . (canceled)  
     
     
         23 . A method for treating tissue, comprising; 
 forming a free-standing powder comprising at least one nanocrystalline metal; and    applying the free-standing powder in therapeutically-effective amounts to the tissue which is to be treated,    wherein the tissue comprises at least on e tissue selected from the group consisting of endocardium tissue, pericardium tissue, bone tissue, and joint tissue.    
     
     
         24 - 30 . (canceled)  
     
     
         31 . A method for treating tissue, comprising: 
 forming a solution at a site remote from the tissue which is to be treated by dissolving in water at least one nanocrystalline metal; and    applying the solution in therapeutically effective amounts to the tissue which is to be treated,    wherein the tissue comprises at least one tissue selected from the group consisting of endocardium tissue, pericardium tissue, bone tissue, and joint tissue.    
     
     
         32 - 46 . (canceled)  
     
     
         47 . The method of  claim 1 , wherein the at least nanocrystalline metal comprises nanocrystalline silver.  
     
     
         48 . The method of  claim 23 , wherein the at least nanocrystalline metal comprises nanocrystalline silver.  
     
     
         49 . The method of  claim 31 , wherein the at least nanocrystalline metal comprises nanocrystalline silver.  
     
     
         50 . The method of  claim 49 , wherein the nanocrystalline silver is atomically disordered.  
     
     
         51 . The method of  claim 31 , wherein the at least one nanocrystalline metal is atomically disordered.  
     
     
         52 . The method of  claim 31 , wherein the solution is applied by passing it through a catheter to the tissue which is to be treated.  
     
     
         53 . The method of  claim 31 , wherein the solution is applied by injection into the tissue which is to be treated.  
     
     
         54 . The method of  claim 53 , wherein injection is effected by the use of a needle.  
     
     
         55 . The method of  claim 53 , wherein injection is needle-less injection.  
     
     
         56 . The method of  claim 31 , wherein the solution is applied by injection into a body cavity so as to contact the tissue which is to be treated.