US2006105991A1PendingUtilityA1

Medical composition for protuberance of epithelium

64
Assignee: SEIKAGAKU KOGYO CO LTDPriority: Nov 5, 2001Filed: Jan 4, 2006Published: May 18, 2006
Est. expiryNov 5, 2021(expired)· nominal 20-yr term from priority
Inventors:Shin IshikawaJunichi Onaya
A61K 31/728A61K 31/726A61P 41/00
64
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Claims

Abstract

A medical composition for protuberance of epithelium, which comprises a solution comprising a polysaccharide or a medically acceptable salt thereof, wherein the solution has a viscosity of: (1) from 50 to 500 mPa·s at a shear rate of from 7.7 to 10.0 s −1 ; (2) from 45 to 300 mPa·s at a shear rate of from 19.2 to 20.0 s −1 ; and (3) from 40 to 200 mPa·s at a shear rate of from 38.3 to 40.0 s −1 , when measured using a rotational viscometer at 25° C., and a syringe filled with the medical composition.

Claims

exact text as granted — not AI-modified
1 - 16 . (canceled)  
   
   
       17 . A method for resecting epithelium, which comprises: 
 administering an effective amount of a medical composition to under epithelium to thereby obtain protuberance of the epithelium; and    resecting the protuberance,    wherein the medical composition comprises a solution comprising sodium hyaluronate having a weight average molecular weight of from 700,000 to 1,200,000 and its concentration in the solution is from 0.35 to 0.44% (w/v).    
   
   
       18 . A method for resecting epithelium, which comprises: 
 administering an effective amount of a medical composition to under epithelium to thereby obtain protuberance of the epithelium; and    resecting the protuberance,    wherein the medical composition comprises a solution comprising sodium hyaluronate having a weight average molecular weight of from 1,900,000 to 3,000,000 and its concentration in the solution is from 0.15 to 0.34% (w/v).    
   
   
       19 . The method according to claim  1 , wherein the epithelium is mucosa.  
   
   
       20 . The method according to claim  2 , wherein the epithelium is mucosa.  
   
   
       21 . The method according to claim  3 , wherein the mucosa is digestive organ mucosa.  
   
   
       22 . The method according to claim  4 , wherein the mucosa is digestive organ mucosa.  
   
   
       23 . The method according to claim  1 , which is used for a mucosal resection.  
   
   
       24 . The method according to claim  2 , which is used for a mucosal resection.  
   
   
       25 . The method according to claim  1 , wherein the composition is stored in a syringe prior to use.  
   
   
       26 . The method according to claim  2 , wherein the composition is stored in a syringe prior to use.

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