Trombin-carrying bioabsorbable synthetic nonwoven fabric

Abstract

A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention may be prepared by a process which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric. The bioabsorbable synthetic nonwoven fabric holding thrombin in accordance with the present invention allows for quicker and more effective hemostasis.

1 . A bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient.  
     
     
         2 . The bioabsorbable synthetic nonwoven fabric according to  claim 1 , wherein said bioabsorbable synthetic nonwoven fabric is made of a material selected from the group consisting of polyglycolic acid, polylactic acid and a copolymer of glycolic acid and lactic acid.  
     
     
         3 . The bioabsorbable synthetic nonwoven fabric according to  claim 2 , wherein said material is polyglycolic acid.  
     
     
         4 . The bioabsorbable synthetic nonwoven fabric according to  claim 1 , wherein the thrombin is thrombin derived from human blood or a recombinant human thrombin produced by a recombinant DNA technique.  
     
     
         5 . A hemostatic that uses the bioabsorbable synthetic nonwoven fabric as set forth in  claim 1 .  
     
     
         6 . A process for preparing a bioabsorbable synthetic nonwoven fabric holding thrombin which comprises the steps of immersing a bioabsorbable synthetic nonwoven fabric into a solution containing thrombin and of lyophilizing the obtained nonwoven fabric.  
     
     
         7 . The process according to  claim 6 , wherein said bioabsorbable synthetic nonwoven fabric is made of a material selected from the group consisting of polyglycolic acid, polylactic acid and a copolymer of glycolic acid and lactic acid.  
     
     
         8 . The process according to  claim 7 , wherein said material is polyglycolic acid.  
     
     
         9 . The process according to  claim 6 , wherein the thrombin is thrombin derived from human blood or a recombinant human thrombin produced by a recombinant DNA technique.