Method of increasing systemic tryptophan with niacin compounds

Abstract

Chronic infection with retroviruses, such as HIV, induce a number of metabolic derangements. The present invention relates to a method for increasing systemic tryptophan with niacin compounds.

1 . A method of increasing systemic tryptophan comprising the administration of an effective amount of niacin for increasing systemic tryptophan to a patient in need of an increase in systemic tryptophan wherein the patient is infected with a retrovirus and wherein the patient has a diet that includes at least the RDA (recommended daily allowance) of niacin and tryptophan, wherein the effective amount is approximately 100 milligrams per day.  
   
   
       2 . The method of increasing systemic tryptophan in  claim 1  wherein the effective amount is approximately 500 milligrams per day.  
   
   
       3 . A method of increasing systemic tryptophan comprising the administration of an effective amount of niacin to a patient in need of an increase in systemic tryptophan wherein the effective amount is at least 100 milligrams per day.  
   
   
       4 . The method of increasing systemic tryptophan in  claim 3  wherein the effective amount is at least 500 milligrams per day.  
   
   
       5 . A method of increasing systemic tryptophan comprising the administration of a pharmacological dose of niacin to a patient in need of an increase in systemic tryptophan wherein the pharmacological dose is at least 100 milligrams per day.  
   
   
       6 . The method of increasing systemic tryptophan in  claim 5  wherein the pharmacological dose is at least 500 milligrams per day.