Fluoroether compositions and methods for inhibiting their degradation in the presence of a lewis acid

Abstract

The present invention relates to an anesthetic composition containing a fluoroether compound and a physiologically acceptable Lewis acid inhibitor. This composition exhibits improved stability and does not readily degrade in the presence of a Lewis acid.

1 . A method of stabilizing an anesthetic composition including sevoflurane, comprising the step of inhibiting the interaction of said sevoflurane with a Lewis acid.  
   
   
       2 . A method according to  claim 1  wherein said inhibition step is achieved by a barrier formed by a physiologically acceptable inhibitor.  
   
   
       3 . A method according to  claim 2  wherein said barrier is a chemical barrier.  
   
   
       4 . A method according to  claim 3  wherein said physiological acceptable inhibitor is a chemical inhibitor.  
   
   
       5 . A method according to  claim 4  wherein said chemical inhibitor is a Lewis acid inhibitor.  
   
   
       6 . A method according to  claim 5  wherein said Lewis acid inhibitor is provided in a liquid form.  
   
   
       7 . A method according to  claim 5  wherein said Lewis acid inhibitor is provided by a coating supported within a container having said sevoflurane.  
   
   
       8 . A method according to  claim 7  wherein said Lewis acid inhibitor is in solid form.  
   
   
       9 . A method according to  claim 5  wherein said Lewis acid inhibitor is water.  
   
   
       10 . A method according to  claim 9  wherein said water may be selected from a group consisting of distilled water, purified water, and combinations thereof.