US2006171885A1PendingUtilityA1

Skin or hair binding peptides

57
Assignee: JANSSEN GISELLEPriority: Nov 25, 2002Filed: Nov 12, 2003Published: Aug 3, 2006
Est. expiryNov 25, 2022(expired)· nominal 20-yr term from priority
Inventors:Giselle JanssenChristopher J. MurrayDeborah S. Winetzky
C07K 7/06C12N 15/1037A61Q 5/02A61K 8/64C07K 1/047C07K 7/08
57
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The invention is directed to peptides. Specifically, the invention is directed to peptides which bind skin and do not bind hair. Alternatively, the invention is drawn to peptides which bind hair and do not bind skin.

Claims

exact text as granted — not AI-modified
1 . A skin binding peptide including (a) any one of SEQ ID NOs. 1-24 or (b) an amino acid sequence having at least 50% sequence identity to any one sequence of SEQ ID NOs. 1-24 and including a sequence cluster selected from the group consisting of APQQRPMXTXXX (SEQ ID NO. 25); PPWXXXL (SEQ ID NO. 26); XXTXLTS (SEQ ID NO. 27); XPPLLXL (SEQ ID NO. 28); SXPSGAX (SEQ ID NO. 29); XQATFXXNXXXX (SEQ ID NO. 30); VXTSQLXXXXXX (SEQ ID NO. 31); LXXXRMK (SEQ ID NO. 32), and HXXXYLT (SEQ ID NO. 33), wherein X represents any L-amino acid.  
     
     
         2 . The skin binding peptide according to  claim 1 , wherein the peptide has at least 90% sequence identity to any of SEQ ID NOs. 1-24.  
     
     
         3 . The skin binding peptide according to  claim 1 , wherein the peptide has at least 95% sequence identity to any of SEQ ID NOs. 1-24.  
     
     
         4 . The skin binding peptide according to  claim 1 , wherein the peptide includes amino acid SEQ ID NO1.  
     
     
         5 . The skin binding peptide according to  claim 1 , wherein the peptide includes amino acid SEQ ID NO. 3.  
     
     
         6 . The skin binding peptide according to  claim 1 , wherein the peptide includes amino acid SEQ ID NO. 5.  
     
     
         7 . The skin binding peptide according to  claim 1 , wherein the peptide includes amino acid SEQ ID NO. 6.  
     
     
         8 . The skin binding peptide according to  claim 1 , wherein the peptide includes amino acid SEQ ID NO. 8.  
     
     
         9 . The skin binding peptide according to  claim 1 , wherein the peptide includes amino acid sequence SEQ ID NO. 15.  
     
     
         10 . The skin binding peptide according to  claim 1 , wherein the peptide includes the sequence cluster APQQRPMXTXXX (SEQ ID NO. 25).  
     
     
         11 . The skin binding peptide according to  claim 1 , wherein the peptide includes the sequence cluster XQATFXXNXXXX (SEQ ID NO. 30).  
     
     
         12 . The skin binding peptide according to  claim 1 , wherein the peptide includes the sequence cluster LXXXRMK (SEQ ID NO. 32).  
     
     
         13 . The skin binding peptide according to  claim 1 , wherein the peptide includes a C-C derivative.  
     
     
         14 . A composition comprising any one of the skin binding peptides according to  claim 1 .  
     
     
         15 . A hair binding peptide including (a) any one of SEQ ID NOs. 34-56 or (b) an 
 amino acid sequence having at least 50% sequence identity to any one sequence of SEQ ID NOs. 34-56 and including a sequence cluster selected from the group consisting of NTPXXNX (SEQ ID NO. 57); PXXXLST (SEQ ID NO. 58); TXPTHR (SEQ ID NO. 59); LXTXSTP (SEQ ID NO. 60); and TPLTXXT (SEQ ID NO. 61) and XQXHNPP (SEQ ID NO. 62), wherein X represents any L-amino acid.    
     
     
         16 . The hair binding peptide according to  claim 1 , wherein said peptide has at least 90% sequence identity to any of SEQ ID NOs. 34-56.  
     
     
         17 . The hair binding peptide according to  claim 1 , wherein the peptide has at least 95% sequence identity to any of SEQ ID NOs. 34-56.  
     
     
         18 . The hair binding peptide according to  claim 15 , wherein the hair binding peptide includes the sequence cluster NTPXXNX (SEQ ID NO. 57).  
     
     
         19 . The hair binding peptide according to  claim 15 , wherein the hair binding peptide includes the sequence cluster PXXXLST (SEQ ID NO. 58).  
     
     
         20 . The hair binding peptide according to  claim 15 , wherein the hair binding peptide includes the sequence cluster TXPTHR (SEQ ID NO. 59).  
     
     
         21 . The hair binding peptide according to  claim 15 , wherein the hair binding peptide includes the sequence cluster LXTXSTP (SEQ ID NO. 60).  
     
     
         22 . The hair binding peptide according to  claim 15 , wherein the hair binding peptide includes the sequence cluster TPLTXXT (SEQ ID NO. 61).  
     
     
         23 . The hair binding peptide according to  claim 15 , wherein the hair binding peptide includes the sequence cluster XQXHNPP (SEQ ID NO. 62).  
     
     
         24 . A composition comprising at least one hair binding peptide according to  claim 15.

Join the waitlist — get patent alerts

Track US2006171885A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.