Integrated vascular device with puncture site closure component and sealant and methods of use

Abstract

Apparatus and methods are provided for use in sealing a vascular puncture site. The invention comprises an integrated vascular device having a sheath with a closure component and puncture sealant. The closure component is disposed on and advanceable over the exterior of the sheath and may comprise any of a variety of apparatus suited for closing a vascular puncture. Once the closure component has been actuated to close the puncture, sealant is introduced to seal the puncture. The sheath and closure component are then removed from the patient.

1 . A device for closing an opening in tissue, comprising: 
 an elongate tubular member having first and second ends and having a lumen extending therethrough;    a first jaw associated with the second end of the elongate tubular member;    a second jaw pivotally associated with the tubular member and disposed adjacent to the second end of the elongate tubular member and the first jaw; and    a plunger having a proximal end and a distal end, wherein the plunger is disposed within the lumen of the tubular member, wherein the distal end of the plunger is associated with the second jaw.    
   
   
       2 . The device of  claim 1 , further comprising a clip.  
   
   
       3 . The device of claims wherein the clip is retained within a channel, the channel defined as a space between the first and second jaws.  
   
   
       4 . The device of  claim 3 , wherein the second jaw is movable between a first and second position, the second jaw retained in said second position by a biasing member.  
   
   
       5 . The device of  claim 3 , wherein the plunger is movable between a first and second position, wherein when disposed in the second position the plunger moves the second jaw from said second position to said first position.  
   
   
       6 . The device of  claim 5 , wherein the clip is bioabsorbable.  
   
   
       7 . A device for closing an opening in tissue, comprising: 
 an elongate tubular member having a first end, a second end, and a lumen extending from the first end toward the second end;    a first jaw formed by the second end of the elongate tubular member;    a second jaw pivotally mounted to the tubular member and movable relative to the first jaw; and    a plunger having a proximal end and a distal end, the plunger being slidably received within the lumen and selectively engages the second jaw to move the second jaw relative to the first jaw.    
   
   
       8 . The device of  claim 7 , wherein the second jaw comprises a moment arm movable as the plunger moves within the lumen.  
   
   
       9 . The device of  claim 7 , wherein the second jaw is moveable between an open position and a closed position.  
   
   
       10 . The device of  claim 9 , further comprising a biasing member extending between the elongate tubular member and the second jaw, the biasing member applying a biasing force to the second jaw to maintain the second jaw in the closed position.  
   
   
       11 . The device of  claim 10 , wherein the plunger is movable between a first position and a second position, wherein when disposed in the second position the plunger moves the second jaw from the closed position to the open position.  
   
   
       12 . The device of  claim 7 , further comprising a clip.  
   
   
       13 . The device of  claim 12 , wherein the clip is retained by the first jaw and the second jaw when the second jaw is in a closed position.  
   
   
       14 . The device of  claim 12 , wherein the clip is bioabsorbable.  
   
   
       15 . The device of  claim 12 , wherein the clip is implantable.  
   
   
       16 . A device for closing an opening in tissue, comprising: 
 an elongate tubular member having first and second ends and having a lumen extending therethrough;    a first jaw associated with the second end of the elongate tubular member;    a second jaw pivotally associated with the tubular member and disposed adjacent to the first jaw; and    a plunger movable within the lumen of the elongate tubular member, the plunger having a proximal end and a distal end comprising a release arm, the release arm selectively engaging the second jaw as the plunger selectively moves within the lumen.    
   
   
       17 . The device of  claim 16 , further comprising a clip retained between the first jaw and the second jaw.  
   
   
       18 . The device of  claim 17 , wherein the clip is either bioabsorbable or implantable.  
   
   
       19 . The device of  claim 18 , wherein the plunger is movable between a first position and a second position, wherein when disposed in the second position the plunger moves the second jaw from the second position to the first position to release the clip.  
   
   
       20 . The device of  claim 19 , wherein the second jaw is biased to remain in the second position by a means for biasing.