Recombinant SP-A for the treatment or prevention of pulmonary infection and inflammation

Abstract

Recombinant surfactant protein A and medicament compositions based thereon are useful for the prevention or treatment of pulmonary infection and inflammation.

1 .- 17 . (canceled)  
     
     
         18 . A lipid-free pharmaceutical composition in powder form comprising a pharmaceutically acceptable active component and a suitable carrier therefore, wherein the active component comprises recombinant surfactant protein A (rSP-A).  
     
     
         19 . The pharmaceutical composition of  claim 18 , wherein the rSP-A is obtained by expression of a genomic sequence coding for SP-A in a suitable expression system.  
     
     
         20 . The pharmaceutical composition of  claim 18 , wherein the rSP-A is obtained by expression of a cDNA coding for SP-A in a suitable expression system.  
     
     
         21 . An article of manufacture comprising packaging material and the pharmaceutical composition according to  claim 18  contained within the packaging material, wherein the packaging material comprises a label or package insert which indicates that the active component is useful for treating a pulmonary microbial infection or inflammation.