Remedies

Abstract

The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring enhancement of NGF production, wherein the compound has a coumarin and/or chroman backbone. Since no toxicity is especially found in the effective ingredient of the present invention, and there is no risk of incidence of adverse actions, the treatment or the like of the above disease can be safely and appropriately carried out.

1 . A method for enhancing nerve growth factor production, said method comprising administering to an animal at least one isolated or purified compound selected from the group consisting of a compound having a coumarin backbone, a compound having a 2-dimethyl chroman backbone, and pharmacologically acceptable salts thereof.  
     
     
         2 . The method according to  claim 1 , wherein the compound having the coumarin backbone is represented by the general formula (I):  
       
         
           
           
               
               
           
         
         wherein each of R 1 , R 2  and R 3  is a hydrogen atom, hydroxyl group, an aliphatic group, an aromatic group, an aromatic-aliphatic group or a saccharide residue, which may be identical or different;  
         or the compound having the coumarin backbone is represented by the general formula (II):  
         
           
             
             
                 
                 
             
           
         
         wherein each of R 4  and R 5  is a hydrogen atom, hydroxyl group, an R i O group, an R ii COO group, R i  and R ii  being an aliphatic group or an aromatic group, or a saccharide residue, which may be identical or different.