Titanium oxide-organic polymer conjuction suitable for artificial bone

Abstract

The titanium oxide-organic polymer composite material for artificial bone obtained by forming titania gel on the surface of said base material by titania solution treatment to dip into a solution of 0° C. to 50° C. temperature for from several seconds to 1 week obtained by adding a solution consisting of acidic alcohol and water into alcohol solution of titaniumtetraalcoxide to a base material composed of a polymer compound selected from a group consisting of polyolefin, polyester and nylon, and modifying to a titanium oxide membrane which forms apatite having similar Ca/P atom ratio to an apatite of mammalian's bone in supersaturated aqueous solution to apatite or from a body fluid of mammalian by dipping said base material on the surface of which titania gel is formed into hot water of 50° C. to 95° C. or solution of room temperature to 95° C. to which acid is added.

1 . A titanium oxide-organic polymer composite material for artificial bone obtained by forming titania gel on the surface of said base material by titania solution treatment to dip into a solution of 0° C. to 50° C. temperature for from several seconds to 1 week obtained by adding a solution consisting of acidic alcohol and water into alcohol solution of titaniumtetraalcoxide to a base material composed of a polymer compound selected from a group consisting of polyolefin, polyester and nylon, and modifying to a titanium oxide membrane which forms apatite having similar Ca/P atom ratio to an apatite of mammalian's bone in supersaturated aqueous solution to apatite or from a body fluid of mammalian by dipping said base material on the surface of which titania gel is formed into hot water of 50° C. to 95° C. or solution of room temperature to 95° C. to which acid is added.  
   
   
       2 . The titanium oxide-organic polymer composite material for artificial bone of  claim 1 , wherein titaniumtetraalcoxide is tetraisopropyltitanate, alcohol is ethanol and acid is inorganic acid.  
   
   
       3 . The titanium oxide-organic polymer composite material for artificial bone of  claim 1 , wherein polyolefin is low-density polyethylene, polyester is polyethyleneterephthalate and nylon is 6-nylon.  
   
   
       4 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 1 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       5 . A composite for artificial bone prepared by obtaining a titanium oxide-organic polymer composite material for artificial bone obtained by forming titania gel on the surface of said base material by titania solution treatment characterizing dipping into a solution of 0° C. to 10° C. temperature for from several seconds to 1 week obtained by adding a solution consisting of acidic alcohol and water into alcohol solution of titaniumtetraalcoxide to a base material composed of a polymer compound selected from a group consisting of polyolefin, polyester and nylon, and modifying to a titanium oxide membrane which forms apatite having similar Ca/P atom ratio to an apatite of mammalian's bone in supersaturated aqueous solution to apatite or from a body fluid of mammalian by dipping said base material on the surface of which titania gel is formed into hot water of 50° C. to 95° C. or solution of room temperature to 95° C. to which acid is added, then forming an apatite by dipping said composite into supersaturated aqueous solution to apatite.  
   
   
       6 . The composite material for artificial bone of  claim 5 , wherein titaniumtetraalcoxide is tetraisopropyltitanate, alcohol is ethanol and acid is inorganic acid.  
   
   
       7 . The composite material for artificial bone of  claim 5 , wherein titanium oxide-organic polymer for artificial bone is obtained by using low-density polyethylene as polyolefin, polyethyleneterephthalate as polyester and 6-nylon as nylon.  
   
   
       8 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 5 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       9 . The titanium oxide-organic polymer composite material for artificial bone of  claim 2 , wherein polyolefin is low-density polyethylene, polyester is polyethyleneterephthalate and nylon is 6-nylon.  
   
   
       10 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 2 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       11 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 3 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       12 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 9 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       13 . The composite material for artificial bone of  claim 6 , wherein titanium oxide-organic polymer for artificial bone is obtained by using low-density polyethylene as polyolefin, polyethyleneterephthalate as polyester and 6-nylon as nylon.  
   
   
       14 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 6 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       15 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 7 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.  
   
   
       16 . The titanium oxide-organic polymer composite material for artificial bone according to  claim 13 , wherein the solution for titania solution treatment is prepared by dipping a solution composed of acidic alcohol and water to a solution of titaniumtetraalcoxide and alcohol maintaining the temperature to 0° C. to 10° C.