US2006204987A1PendingUtilityA1

Applications with and methods for producing selected interstrand cross-links in nucleic acids

Assignee: VOLKERS HERMANPriority: Dec 3, 1998Filed: Feb 15, 2006Published: Sep 14, 2006
Est. expiryDec 3, 2018(expired)· nominal 20-yr term from priority
C07H 21/04C12Q 1/6841C12Q 1/6832C12Q 1/6816C12Q 1/686
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Claims

Abstract

The invention provides a method for stably cross-linking a first nucleic acid sequence selected for being stably cross-linked in the presence of a second nucleic acid sequence selected for not being stably cross-linked in a nucleic acid molecule. The method comprises providing a nucleic acid sequence that is complementary to the first nucleic acid sequence; hybridizing the first nucleic acid sequence to its complementary sequence; and stably cross-linking the first nucleic acid sequence to the complementary sequence.

Claims

exact text as granted — not AI-modified
1 .- 23 . (canceled)  
   
   
       24 . A method for stably cross-linking a first nucleic acid sequence selected for being stably cross-linked in the presence of a second nucleic acid sequence selected for not being stably cross-linked in a nucleic acid molecule, the method comprising: 
 i) providing a nucleic acid sequence that is complementary to the first nucleic acid sequence;    ii) hybridizing the first nucleic acid sequence to its complementary sequence; and    iii) stably cross-linking the first nucleic acid sequence to the complementary sequence.

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