US2006204987A1PendingUtilityA1
Applications with and methods for producing selected interstrand cross-links in nucleic acids
Est. expiryDec 3, 2018(expired)· nominal 20-yr term from priority
Inventors:Herman VolkersRobert Jochem HeetebrijHendrik Jan HouthoffR.P.M. GijlswijkHendrikus TankeAnton Raap
C07H 21/04C12Q 1/6841C12Q 1/6832C12Q 1/6816C12Q 1/686
54
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Abstract
The invention provides a method for stably cross-linking a first nucleic acid sequence selected for being stably cross-linked in the presence of a second nucleic acid sequence selected for not being stably cross-linked in a nucleic acid molecule. The method comprises providing a nucleic acid sequence that is complementary to the first nucleic acid sequence; hybridizing the first nucleic acid sequence to its complementary sequence; and stably cross-linking the first nucleic acid sequence to the complementary sequence.
Claims
exact text as granted — not AI-modified1 .- 23 . (canceled)
24 . A method for stably cross-linking a first nucleic acid sequence selected for being stably cross-linked in the presence of a second nucleic acid sequence selected for not being stably cross-linked in a nucleic acid molecule, the method comprising:
i) providing a nucleic acid sequence that is complementary to the first nucleic acid sequence; ii) hybridizing the first nucleic acid sequence to its complementary sequence; and iii) stably cross-linking the first nucleic acid sequence to the complementary sequence.Join the waitlist — get patent alerts
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