Protein biopolymer markers indicative of age matched control

Abstract

The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer, predict disease risk assessment, and develop therapeutic avenues against said disease.

1 . A method for screening for efficacy of disease process modulating agents for Alzheimer's disease comprising: 
 (a) providing a sample of bodily fluid containing a biopolymer marker consisting of SEQ ID NO:3;    (b) adding a quantity of said agent sufficient to interact with said biopolymer marker consisting of SEQ ID NO:3; and    (c) determining the presence of an interaction between said agent and said biopolymer marker consisting of SEQ ID NO:3;    wherein said interaction is determinative of efficacy of said disease process modulating agent.    
     
     
         2 . A method for diagnosing Alzheimer's disease comprising: 
 (a) providing a sample; and    (b) determining a presence of a biopolymer marker consisting of SEQ ID NO:3 in said sample;    wherein the presence of said biopolymer marker consisting of SEQ ID NO:3 is diagnostic for Alzheimer's disease.