Long-wearable soft contact lens

Abstract

A mold for producing a soft contact lens, wherein the mold is capable of forming both front and rear surfaces of the lens from a surface of the mold during polymerization of a monomer composition.

1 . A mold for producing a contact lens, wherein said mold is capable of forming both front and rear surfaces of said contact lens from a surface of said mold during polymerization of a monomer composition in said mold and comprises a resin of polyethylene terephthalate.  
     
     
         2 . A mold for producing a contact lens, wherein said mold is capable of forming both front and rear surfaces of said contact lens from a surface of said mold during polymerization of a monomer composition in said mold and comprises a resin of an ethylene-vinylalcohol copolymer with an ethylene copolymerization ratio of about 25-50% by mole.  
     
     
         3 . A Contact lens produced by the mold according to  claim 1 , wherein said contact lens is a hydrogel soft contact lens manufactured by a polymerization of at least one kind of siloxane monomer.  
     
     
         4 . A Contact lens produced by the mold according to  claim 1 , wherein said contact lens is a hydrogel soft contact lens manufactured by a copolymerization of at least one kind of hydrophilic polysiloxane monomer of the formula (1) and at least one kind of a hydrophilic monomer:  
       
         
           
           
               
               
           
         
         wherein, X1 is a polymerizable substituent shown by the following formula (2);  
         
           
             
             
                 
                 
             
           
         
         wherein, R5 is a hydrogen or a methyl group; Z1 is a linking group selected from —NHCOO—, —NHCONH—, —OCONH—R6-NHCOO—, —NHCONH—R7-NHCONH— and —OCONH—R8-NHCONH— (R6, R7 and R8 are hydrocarbon groups with 2-13 carbon atoms); m is 0-10; n is 3-10; p is 0 when m is 0 and 1 when m is not less than 1; q is an integer of 0-20; R1, R2, R3 and R4 are groups independently selected from hydrocarbon groups with 1-12 carbon atoms or trimethylsiloxy group; and the structure [Y1] shows a polysiloxane backbone comprising not less than 2 siloxane linkages.  
       
     
     
         5 . A Contact lens produced by the mold according to  claim 1 , wherein said contact lens is a contact lens manufactured by a copolymerization of at least a kind of siloxane group-containing monomer and at least one kind of hydrophilic monomer.  
     
     
         6 . A method for producing a hydrogel soft contact lens comprising polymerizing at least one siloxane monomer, said mold comprising a resin selected from the group consisting of nylon 66, nylon 6, polyethylene terephthalate and ethylene-vinyl alcohol copolymer.  
     
     
         7 . The method according to  claim 6 , wherein said mold comprises ethylene-vinyl alcohol copolymer.  
     
     
         8 . A method for producing a contact lens comprising copolymerizing at least one siloxane monomer and at least one hydrophilic monomer, said mold comprising a resin selected from the group consisting of nylon 66, nylon 6, polyethylene terephthalate and ethylene-vinyl alcohol copolymer.  
     
     
         9 . The method according to  claim 8 , wherein said mold comprises ethylene-vinyl alcohol copolymer.  
     
     
         10 . The mold according to  claim 1 , which comprises an enhanced crystallinity polyethylene terephthalate.  
     
     
         11 . The mold according to  claim 1 , which comprises a drawn film of polyethylene terephthalate.  
     
     
         12 . A method for producing a contact lens comprising photopolymerization by irradiating said mold with a light, said mold comprising a resin selected from the group consisting of nylon 66,-nylon 6, polyethylene terephthalate and ethylene-vinyl alcohol copolymer.  
     
     
         13 . The method according to  claim 12 , wherein said mold comprises ethylene-vinyl alcohol copolymer.  
     
     
         14 . A mold for directly producing a contact lens, comprising a surface capable of forming both front and rear surfaces of said contact lens during polymerization of a monomer composition, and wherein the mold material is a resin selected from the group consisting of polyamide, polyethylene terephthalate and ethylene-vinyl alcohol copolymer, and wherein at least one side of the mold for forming the lens surface has a contact angle to water not higher than 90°.  
     
     
         15 . A hydrophilic polysiloxane monomer represented by the formula (1):  
       
         
           
           
               
               
           
         
       
       wherein X is a polymerizable substituent shown by the formula (2):  
       
         
           
           
               
               
           
         
       
       wherein R5 is hydrogen or a methyl group; Z1 is a linking group selected from —NHCOO—, —NHCONH—, —OCONH—R6-NHCOO—, NHCONH—R7-NHCONH— and —OCONH—R8-NHCONH— wherein R6, R7 and R8 are hydrocarbon groups with 2-13 carbon atoms; m is 1-10, n is 3-10, q is an integer of 0-20; R1, R2, R3 and R4 are independently groups selected from hydrocarbon groups with 1-12 carbon atoms or trimethylsiloxy group, the structural unit [Y1] comprises linked structural unit (Ic), (IIc) and (IIIc) shown by the following formulas:  
       
         
           
           
               
               
           
         
       
       wherein R19 is selected from the groups of the following formulas (3) and (4):  
         —C 3 H 6 (OC 2 H 4 )OH   (3)  —C 3 H 6 (OC 2 H 4 ) d OCH 3    (4)  
       wherein c and d are 2-40, 
 the linkage ratio of the structural units (Ic), (IIc) and (IIIC) being ((Ic)+(IIc))/(IIIc)=0.5-100, (IIc)/(Ic)=0-1, and the total number of the units (Ic), (IIc) and (IIIC) being 10-1000.  
 
     
     
         16 . The hydrophilic polysiloxane monomer according to  claim 15 , wherein the linkage ratio of the structural units (Ic), (IIc) and (IIIc) is ((Ic)+(IIc))/(IIIc)=1-50, (IIc)/(Ic)=0.01-0.5, and the total number of the units (Ic), (IIc) and (IIIc) is 20-500.  
     
     
         17 . The hydrophilic polysiloxane monomer according to  claim 15 , wherein said Z1 in the formula (2) in  claim 15  is —NHCOO—.  
     
     
         18 . The hydrophilic polysiloxane monomer according to  claim 15 , wherein m in formula (2) is 2.  
     
     
         19 . The hydrophilic polysiloxane monomer according to  claim 15 , wherein said n in formula (2) in is 3.  
     
     
         20 . The hydrophilic polysiloxane monomer according to  claim 15 , wherein said q in formula (2) is 1.  
     
     
         21 . The hydrophilic polysiloxane monomer according to  claim 15 , wherein the average of d in formula (4) is about 7.  
     
     
         22 . An ophthalmic lens materials comprising the monomer according to  claim 15 .  
     
     
         23 . A contact lens materials comprising the monomer according to claim 15.