US2006229288A1PendingUtilityA1

Inhibitors of phosphodiesterases in infertility

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Assignee: PALMER STEPHEN SPriority: Apr 1, 2003Filed: Feb 28, 2006Published: Oct 12, 2006
Est. expiryApr 1, 2023(expired)· nominal 20-yr term from priority
Inventors:Stephen PalmerSean D. MckennaStephen John ArkinstallAliza EshkolMichael C. Macnamee
A61P 43/00A61K 31/519A61K 45/06A61P 15/00A61K 31/53A61P 15/08A61K 31/505A61K 38/24A61K 38/09A61K 31/517A61K 45/00
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Claims

Abstract

The present invention is directed to methods of increasing oocyte production in a mammal. More specifically, the specification describes methods and compositions for inducing follicular maturation using a PDE inhibitor. The inhibitor may be used alone at high doses. Alternatively, the follicular maturation is achieved by combining a low dose of FSH with the PDE inhibitor treatment.

Claims

exact text as granted — not AI-modified
1 . A method for stimulating ovarian follicular growth in a female, comprising administering to a female a medicament comprising a phosphodiesterase (PDE) inhibitor.

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