US2006235082A1PendingUtilityA1

Long-chain, straight-chain 2-amino-3-hydroxyalkanes

Assignee: RINEHART KENNETH LPriority: Apr 15, 1997Filed: Jun 15, 2006Published: Oct 19, 2006

Est. expiryApr 15, 2017(expired)· nominal 20-yr term from priority

Inventors:Kenneth L. Rinehart Robert A. Warwick Jesus Avila Nancy Fregeau Dolores Garcia Gravalos Glynn Thomas Faircloth

A61K 35/618C07B 2200/07C07C 215/08

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Abstract

Investigation of the activity of extracts of the clam Spisula polynyma has led to antitumor long-chain, straight-chain alkane compounds which have a 2-amino group and a 3-hydroxy group. Compositions and methods comprising an isolated and purified long-chain, straight-chain 2-amino-3-hydroxyalkane, or prodrug thereof, and a pharmaceutically acceptable carrier are also described, wherein the carbon chain in the long-chain, straight-chain 2-amino-3-hydroxyalkane is C 16 -C 24 .

Claims

exact text as granted — not AI-modified

1 . A C 16 -C 24  compound of Formula II:  
     
       
         
         
             
             
         
       
     
     where n is not 12.  
   
   
       2 . The compound according to  claim 1 , where n=10.  
   
   
       3 . The compound according to  claim 1 , where n=14-18.

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