Cosmetic and dermopharmaceutical compositions for skin prone to acne

Abstract

The invention relates to the use of an extract of olive leaves ( Olea europaea ) which is titrated in oleanolic acid and which may or may not be associated with a Larrea divaricata extract which is titrated in nordihydroguaiaretic acid (NDGA). Said products are intended for all types of cosmetic and dermopharmaceutical compositions for all forms of skin care, for moisturizing and anti-inflammatory purposes and, in particular, for the prevention and treatment of skin prone to acne.

1 . A method of treating acne-prone skin comprising the steps of providing a cosmetic or dermopharmaceutical composition comprising an effective quantity of oleanolic acid, wherein said effective quantity is between about 1 ppm and about 10,000 ppm, and applying said composition to skin in need thereof.  
     
     
         2 . The method of  claim 1 , wherein said effective quantity of oleanolic acid is between about 10 ppm and about 1,000 ppm.  
     
     
         3 . The method of  claim 1 , wherein said composition further comprises nordihydroguaiaretic acid.  
     
     
         4 . The method of  claim 3 , wherein said nordihydroguaiaretic acid is between about 1 and about 10,000 ppm.  
     
     
         5 . The method of  claim 1 , wherein said composition further comprises at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin.  
     
     
         6 . The method of  claim 5 , wherein said at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin is selected from the group consisting of keratolytic, sebum-regulating, moisturizing and osmotic active substances.  
     
     
         7 . A method of treating skin inflammation in the skin of a subject in need thereof comprising the steps of providing a cosmetic or dermopharmaceutical composition comprising an effective quantity of oleanolic acid, wherein said effective quantity is between about 1 ppm and about 10,000 ppm, and applying said composition to skin in need thereof.  
     
     
         8 . The method of  claim 7 , wherein said effective quantity of oleanolic acid is between about 10 ppm and about 1,000 ppm.  
     
     
         9 . The method of  claim 7 , wherein said composition further comprises nordihydroguaiaretic acid.  
     
     
         10 . The method of  claim 9 , wherein said nordihydroguaiaretic acid is between about 1 and about 10,000 ppm.  
     
     
         11 . The method of  claim 7 , wherein said composition further comprises at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin.  
     
     
         12 . The method of  claim 11 , wherein said at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin is selected from the group consisting of keratolytic, sebum-regulating, moisturizing and osmotic active substances.  
     
     
         13 . A method of treating or preventing symptoms of acne or hyperseborrhea comprising the steps of providing a cosmetic or dermopharmaceutical composition comprising an effective quantity of oleanolic acid, wherein said effective quantity is between about 1 ppm and about 10,000 ppm, and optionally nordihydroguaiaretic, and applying said composition to skin in need thereof.  
     
     
         14 . The method of  claim 13 , wherein said effective quantity of oleanolic acid is between about 10 ppm and about 1,000 ppm.  
     
     
         15 . The method of  claim 13 , wherein said nordihydroguaiaretic acid is between about 1 ppm and about 10,000 ppm.  
     
     
         16 . The method of  claim 13 , wherein said composition further comprises at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin.  
     
     
         17 . The method of  claim 16 , wherein said at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin is selected from the group consisting of keratolytic, sebum-regulating, moisturizing and osmotic active substances.  
     
     
         18 . A method of reducing 5a-reductase in the skin of a subject in need thereof comprising the steps of providing a cosmetic or dermopharmaceutical composition comprising an effective quantity of oleanolic acid, wherein said effective quantity is between about 1 ppm and about 10,000 ppm, and administering said an amount of said composition to a portion of said skin of said subject sufficient to reduce the levels of 5α-reductase in said skin of said subject.  
     
     
         19 . The method of  claim 18 , wherein said effective quantity of oleanolic acid is between about 10 ppm and about 1,000 ppm.  
     
     
         20 . The method of  claim 18 , wherein said composition further comprises nordihydroguaiaretic acid.  
     
     
         21 . The method of  claim 20 , wherein said nordihydroguaiaretic acid is between about 1 and about 10,000 ppm.  
     
     
         22 . The method of  claim 18 , wherein said composition further comprises at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin.  
     
     
         23 . The method of  claim 22 , wherein said at least one other ingredient employed in the treatment of acne, hyperseborrhea and acne-prone skin is selected from the group consisting of keratolytic, sebum-regulating, moisturizing and osmotic active substances.