US2006251636A1PendingUtilityA1

Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter

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Assignee: CONNOLLY EAMONNPriority: Oct 7, 2002Filed: Mar 31, 2006Published: Nov 9, 2006
Est. expiryOct 7, 2022(expired)· nominal 20-yr term from priority
A61P 43/00A61P 31/04A61P 29/00A61P 1/06A61P 1/04A23L 33/135A23V 2002/00C12P 21/00C12N 1/20C12R 2001/225C12N 1/205A61K 35/747A23V 2400/173
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Claims

Abstract

Strains of Lactobacillus which have been selected for their capability of reducing gastrointestinal inflammation, such as that due to Helicobacter pylori, and products derived from these strains, including agents for treatment or prophylaxis of inflammation associated with Helicobacter pylori for administration to humans and include conditioned media in which the selected strains have grown and protein-containing extracts of the conditioned media.

Claims

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       3 . A biologically pure culture of a  Lactobacillus  strain selected for its ability to reduce gastrointestinal inflammation associated with  Helicobacter pylori  infection in the gastrointestinal tract in mammals using a [mouse] macrophage assay for TNFα activity.  
   
   
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