US2006275897A1PendingUtilityA1

HIV vaccines based on Env of multiple clades of HIV

Assignee: NABEL GARY JPriority: Sep 15, 2003Filed: Mar 15, 2006Published: Dec 7, 2006

Est. expirySep 15, 2023(expired)· nominal 20-yr term from priority

Inventors:Gary J. Nabel Bimal Chakrabarti Wing-Pui Kong Yue Huang Zengguang Wang Zhi-Yong Yang

C12N 2740/16234C07K 14/005A61P 31/18A61K 39/12C12N 2740/16134A61K 2039/53C12N 2740/16122A61K 39/21C12N 2740/16222C12N 2710/10343A61P 37/04A61K 2039/5256

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Abstract

In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a singlr clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.

Claims

exact text as granted — not AI-modified

1 . A multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade.  
     
     
         2 . Multiclade HIV envelope immunogens.  
     
     
         3 . The vaccine of  claim 1  further comprising V1, V2, V3, or V4 deletions or combinations thereof.

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