Retinoid X receptor-interacting polypeptides and related molecules and methods

Abstract

Disclosed is purified DNA encoding retinoid X receptor-interacting proteins and methods for producing RXR-interacting proteins expressed from such DNA.

1 . Purified DNA comprising a sequence encoding a RXR-interacting protein.  
     
     
         2 . The purified DNA of  claim 1 , wherein said DNA encodes a human RXR-interacting protein.  
     
     
         3 . The DNA of  claim 1 , comprising a DNA sequence substantially identical to the DNA sequence of RIP14-1 shown in  FIG. 4  (SEQ ID NO: 6).  
     
     
         4 . The DNA of  claim 1 , comprising a DNA sequence substantially identical to the DNA sequence of RIP14-2 shown in  FIG. 4  (SEQ ID NO: 14).  
     
     
         5 . The DNA of  claim 1 , comprising a DNA sequence substantially identical to the DNA sequence of RIP15 shown in  FIG. 5  (SEQ ID NO: 7).  
     
     
         6 . The DNA of  claim 1 , comprising a DNA sequence substantially identical to the DNA sequence of RIP110 shown in  FIG. 10  (SEQ ID NO: 8).  
     
     
         7 . The DNA of  claim 1 , comprising a DNA sequence substantially identical to the DNA sequence of RIP13 shown in  FIG. 11  (SEQ ID NO: 9).  
     
     
         8 . A vector comprising the purified DNA of  claim 1 .  
     
     
         9 . A cell containing the purified DNA of  claim 1 .  
     
     
         10 . A method of producing a recombinant RXR-interacting protein comprising, 
 providing a cell transformed with DNA encoding a RXR-interacting protein positioned for expression in said cell;    culturing said transformed cell under conditions for expressing said DNA; and    isolating said recombinant RXR-interacting protein.