Ointment wound spray

Abstract

A spray-on topical wound debrider spray is prepared forming a mist, spray or foam which will not drip significantly after application. The preferred wound debrider is papain. The spray contains a surfactant emulsifier admixture having a composition viscosity of from about 5000 cps to about 50,000 cps and is preferably a fatty alcohol phosphate ester emulsifier composition.

1 - 17 . (canceled)  
     
     
         18 . A method of applying a spray-on pharmaceutical wound debrider composition to a wound comprising dispensing said composition from a container onto said wound, wherein said composition does not drip after application, and wherein said composition comprises a wound debrider.  
     
     
         19 . The method of  claim 18 , wherein the composition further comprises an emollient, a humectant, or a preservative.  
     
     
         20 . The method of  claim 19 , wherein the composition further comprises an emollient, a humectant, and a preservative.  
     
     
         21 . The method of  claim 18 , wherein the composition is in the form of a mist.  
     
     
         22 . The method of  claim 18 , wherein the composition is in the form of a spray.  
     
     
         23 . The method of  claim 18 , wherein the composition is in the form of a foam.  
     
     
         24 . The method of  claim 18 , wherein the composition is contained in a non-aerosol pump container.  
     
     
         25 . The method of  claim 18 , wherein the composition is contained in a pressurized aerosol container.  
     
     
         26 . The method of  claim 18 , wherein the composition is a hydrophilic ointment base.  
     
     
         27 . The method of  claim 18 , wherein the composition is a hydrocarbon ointment base.  
     
     
         28 . The method of  claim 18 , wherein the wound debrider is a proteolytic enzyme.  
     
     
         29 . The method of  claim 28 , wherein the proteolytic enzyme is selected from the group consisting of papain, trypsin, chymo-trypsin, streptokinaise, streptodormase, ficin, pepsin, carboxypeptidase, aminopeptidase, chymopapain, bromelin, thermolysin, thermoase, subtilisin, and collagenase.  
     
     
         30 . The method of  claim 29 , wherein the proteolytic enzyme is trypsin.  
     
     
         31 . The method of  claim 29 , wherein the proteolytic enzyme is collagenase.  
     
     
         32 . The method of  claim 29 , wherein the proteolytic enzyme is papain.  
     
     
         33 . The method of  claim 32 , wherein the composition further comprises urea.  
     
     
         34 . The method of  claim 33 , wherein the composition further comprises chlorophyllin copper complex sodium.  
     
     
         35 . The method of  claim 34 , wherein the composition further comprises water, a humectant, an emollient, a preservative, or a surfactant emulsifier.  
     
     
         36 . The method of  claim 35 , wherein the composition comprises water, a humectant, an emollient, a preservative, and a surfactant emulsifier.  
     
     
         37 . The method of  claim 35 , wherein the composition comprises a surfactant emulsifier.  
     
     
         38 . The method of  claim 37 , wherein the surfactant emulsifier comprises cetearyl alcohol, ceteth-20 phosphate and dicetyl phosphate.  
     
     
         39 . The method of  claim 35 , wherein the composition comprises a humectant.  
     
     
         40 . The method of  claim 39 , wherein the humectant is glycerin  
     
     
         41 . The method of  claim 35 , wherein the composition comprises an emollient.  
     
     
         42 . The method of  claim 41 , wherein the emollient is mineral oil.  
     
     
         43 . A method of applying a spray-on pharmaceutical wound debrider composition to a wound comprising dispensing said composition from a container onto said wound, wherein said composition does not drip after application, and wherein said composition comprises water, papain, urea, mineral oil, glycerin, lactose, methylparaben, propylparaben, sodium hydroxide, and a surfactant emulsifier comprising cetearyl alcohol, ceteth-20 phosphate and dicetyl phosphate.  
     
     
         44 . The method of  claim 43 , wherein the composition further comprises chlorophyllin copper complex sodium.  
     
     
         45 . The method of  claim 43 , wherein the composition further comprises potassium phosphate.  
     
     
         46 . A method of topically treating a wound comprising dispensing an effective amount of a spray-on pharmaceutical wound treatment composition from a container onto said wound, wherein said composition does not drip after application.  
     
     
         47 . The method of  claim 46 , wherein the composition comprises at least one of a wound debrider, a wound cleaner, a wound healing agent, an anti-microbial, or an anti-fungal.  
     
     
         48 . The method of  claim 47 , wherein the composition further comprises an emollient, a humectant, and a preservative.  
     
     
         49 . The method of  claim 46 , wherein the composition is in the form of a mist.  
     
     
         50 . The method of  claim 46 , wherein the composition is in the form of a spray.  
     
     
         51 . The method of  claim 46 , wherein the composition is in the form of a foam.  
     
     
         52 . The method of  claim 46 , wherein the composition is contained in a non-aerosol pump container.  
     
     
         53 . The method of  claim 46 , wherein the composition is contained in a pressurized aerosol container.  
     
     
         54 . The method of  claim 46 , wherein the composition is a hydrophilic ointment base.  
     
     
         55 . The method of  claim 46 , wherein the composition is a hydrocarbon ointment base.  
     
     
         56 . The method of  claim 47 , wherein the wound debrider is a proteolytic enzyme.  
     
     
         57 . The method of  claim 56 , wherein the proteolytic enzyme is selected from the group consisting of papain, trypsin, chymo-trypsin, streptokinaise, streptodormase, ficin, pepsin, carboxypeptidase, aminopeptidase, chymopapain, bromelin, thermolysin, thermoase, subtilisin, and collagenase.  
     
     
         58 . The method of  claim 57 , wherein the proteolytic enzyme is trypsin.  
     
     
         59 . The method of  claim 57 , wherein the proteolytic enzyme is collagenase.  
     
     
         60 . The method of  claim 57 , wherein the proteolytic enzyme is papain.  
     
     
         61 . The method of  claim 60 , wherein the composition further comprises urea.  
     
     
         62 . The method of  claim 61 , wherein the composition further comprises chlorphyllin copper complex sodium.  
     
     
         63 . The method of  claim 61 , wherein the composition further comprises water, a humectant, an emollient, a preservative and a surfactant emulsifier comprising cetearyl alcohol, ceteth-20 phosphate and dicetyl phosphate.  
     
     
         64 . The method of  claim 46 , further defined as a method of debriding a wound.  
     
     
         65 . A method of topically treating a wound comprising dispensing an effective amount of a spray on pharmaceutical wound debrider composition from a container onto said wound, wherein said composition does not drip after application, and wherein said composition comprises water, papain, urea, mineral oil, glycerin, lactose, methylparaben, propylparaben, sodium hydroxide, and a surfactant emulsifier comprising cetearyl alcohol, ceteth-20 phosphate and dicetyl phosphate.  
     
     
         66 . The method of  claim 65 , wherein the composition further comprises chlorophyllin copper complex sodium.  
     
     
         67 . The method of  claim 65 , wherein the composition further comprises potassium phosphate.  
     
     
         68 . The method of  claim 65 , further defined as a method of debriding a wound.