Use of botulinum toxin for treatment of articular pathologies

Abstract

Use of botulinum toxin to obtain a product intended to be administered intramuscular with lissive effect in treating articular pathologies, particularly coxarthrosis, or arthrosis of the hip, epicondylitis of the elbow and rotator muscle cap pathology of the shoulder.

1 . A method comprising, intramuscularly administering botulinum toxin to obtain a lissive and de-contracturating effect in treating rotator muscle cap pathology of the shoulder.  
   
   
       2 . The method as in  claim 1 , wherein the botulinium toxin is selected from at least one member of the group consisting of sub-types A, B, C, D, E, F and G.  
   
   
       3 . The method as in  claim 1 , wherein the botulinum toxin is administered to the patient as one or more respective amounts of the botulinum toxin each respective amount comprising a basic dose of the botulinum toxin.  
   
   
       4 . The method as in  claim 1 , wherein the botulinum toxin is administered as several separate basic doses, or several basic doses can be used simultaneously.  
   
   
       5 . The method as in  claim 1 , comprising administering the botulinum toxin as a composition comprising a mixture of the botulinum toxin and human albumin.  
   
   
       6 . The method as in  claim 1  comprising administering the botulinum toxin as a composition comprising a mixture of the botulinum toxin and lactose.  
   
   
       7 . The method as in  claim 1 , comprising administering the botulinum toxin as a composition comprising a mixture of the botulinum toxin and at least a sodium-based compound.  
   
   
       8 . The method as in  claim 1 , comprising administering the botulinum toxin as a composition comprising a mixture of the botulinum toxin and a physiological solution containing sodium chloride between g 0.45% and 1.0%.  
   
   
       9 . (canceled)  
   
   
       10 . (canceled)  
   
   
       11 . The method of  claim 1 , comprising administering at least the botulinum toxin into at least one of the muscles selected from the group consisting of the supraspinal, the infraspinal, the subspinal and the teres minor.  
   
   
       12 . The method of  claim 1 , wherein the intramuscular administering of the botulinum toxin is guided with an electromyographic guide.  
   
   
       13 . The method as in  claim 3 , wherein the basic dose comprises a quantity of Dysport type A botulinum toxin comprised between 25 and 100 MU.  
   
   
       14 . The method as in  claim 1 , wherein the rotator muscle cap pathology comprises tendinosis of the at least one rotator muscle of the patient selected from the group consisting of the supraspinal, the infraspinal, the subspinal and the teres minor.  
   
   
       15 . The method as in  claim 1 , further comprising providing separate predetermined amounts of the botulinum toxin, wherein each predetermined amount is a basic dose of the botulinum toxin, and combining several of said separate predetermined amounts, wherein the combined predetermined amounts are then administered simultaneously.  
   
   
       16 . The method as in  claim 1 , further comprising providing a predetermined amount of the botulinum toxin comprising several basic doses of the botulinum toxin, wherein the predetermined amount is then administered.  
   
   
       17 . A method for treating the symptom of muscular pressure on a shoulder insertion seat in a patient suffering from rotator muscle cap pathology comprising: 
 administering botulinum toxin into at least one rotator muscle of the patient selected from the group consisting of the supraspinal, the infraspinal, the subspinal and the teres minor, wherein said muscular pressure exerted by said at least one rotator muscle on said shoulder insertion seat is reduced.