Stents with a radioactive surface coating, processes for their production and their use for restenosis prophylaxis

Abstract

The invention relates to radioactive stents, characterized in that the stent is coated on the surface with the radioactive isotope, as well as processes for their production.

1 - 9 . (canceled)  
     
     
         10 . A radioactive stent comprising a radioactive isotope that is fixed on the surface of the stent by an adhesive that is solely a peptide, or a peptide bound to a radioactive isotope complexing agent, a fat bound to a radioactive isotope complexing agent, or gold bound to a thiol-group-containing radioactive isotope complexing agent.  
     
     
         11 . A radioactive stent according to  claim 10 , wherein the radioactive isotope is one or more of Ag, Au, Ba, Bi, C, Co, Cr, Cu, Fe, Gd, Hg, Ho, In, Ir, Lu, Mn, Ni, P, Pb, Pd, Pm, Pt, Re, Rh, Ru, S, Sb, Sc, Sm, Th, Tc or Y.  
     
     
         12 . A radioactive stent according to  claim 10 , wherein the adhesive is a peptide.  
     
     
         13 . A radioactive stent according to  claim 10 , wherein the adhesive is a peptide bound to a radioactive isotope complexing agent.  
     
     
         14 - 28 . (canceled)  
     
     
         29 . A radioactive stent according to  claim 10 , wherein the adhesive is gold bound to a thiol-group-containing radioactive isotope complexing agent.  
     
     
         30 . A radioactive stent according to  claim 10 , wherein the adhesive is a fat bound to a radioactive isotope complexing agent.  
     
     
         31 . A radioactive stent comprising a radioactive isotope that is fixed on the surface of the stent by an adhesive consisting essentially of a peptide, or a peptide bound to a radioactive isotope complexing agent, a fat bound to a radioactive isotope complexing agent, or gold bound to a thiol-group-containing radioactive isotope complexing agent.