Sensation masking composition

Abstract

The present invention provides masking compositions that include a lower alkyl carboxylic acid, e.g. acetic acid. Also provided is a masking composition that includes (a) a lower alkyl carboxylic acid (e.g. acetic acid), a warming sensate (e.g. vanillin or vanillyl butyl ether) and/or a cooling sensate (e.g. menthol or isopulegol).

1 . (canceled)  
     
     
         2 . (canceled)  
     
     
         3 . A masking composition comprising: 
 (a) a carboxylic acid represented by the formula                          wherein A is a hydrogen, C 1 -C 3  alkyl; or a salt thereof; and    (b) a warming sensate.    
     
     
         4 . The masking composition of  claim 3  wherein the warming sensate is a compound selected from the groups consisting of: 
 (a) a compound represented by the following formula:                          wherein A is a unsubstituted, branched or straight-chained C 1 -C 3  alkyl group and B is a hydrogen, or an unsubstituted, branched or straight-chained C 1 -C 7  alkyl group, or a salt thereof;    (b) a compound represented by the formula                          wherein C is an unsubstituted, branched or straight-chained C 2 -C 8  alkyl group, optionally interrupted by an oxygen atom, or a salt thereof; or    (c) a compound selected from the group consisting of capsaicin, gingerol, vanillyl ethyl ether, vanillyl propyl ether, vanillyl butyl ether, vanillyl pentyl ether, vanillyl hexyl ether, vanillyl butyl ether acetate, 4-(1-menthoxymethyl)-2-phenyl-1,3-dioxolan, 4-(1-menthoxymethyl)-2-(3′,4′-dihydroxyphenyl)-1,3-dioxolan, 4-(1-menthoxymethyl)-2-(2′-hydroxy-3′-methoxyphenyl)-1,3-dioxolan, 4-(1-menthoxymethyl)-2-(4′-methoxyphenyl)-1,3-dioxolan, 4-(1-menthoxymethyl)-2-(3′,4′-methylenedioxyphenyl)-1,3-dioxolan, 4-(1-menthoxymethyl)-2-(3′-methoxy-4′-hydroxyphenyl)-1,3-dioxolan, red pepper oil, red pepper oleoresin, ginger oleoresin, nonylic acid vanillyl amide, jambu oleoresin, Zanthoxylum piperitum extract, sanshool I, sanshool II, sanshoamide, black pepper extract, chavicine, piperine, and spilanthol.    
     
     
         5 . The masking composition of  claim 3 , wherein the warming sensate is selected from vanillin, ortho-vanillin, ethyl vanillin, vanillyl acetate, vanillyl isobutyrate, capsicum, nonanoyl vanillyl amide, nonanoic acid vanillyl ether, vanillyl alcohol alkyl ether, isovanillyl alcohol alkyl ether, ethylvanillyl alcohol alkyl ether, isovanillyl alcohol alkyl ether, ethylvanillyl alcohol alkyl ether, substituted benzyl alcohol alkyl ether, 4-(1-menthoxymethyl)-2-(3′-methoxy-4′-hydroxyphenyl)-1,3-dioxolane, vanillin propylene glycol acetal, ethylvanillin, propylene glycol acetal, ginger extract, ginger oil, gingerol, gingerone, and analogs and derivatives of the above.  
     
     
         6 . The masking composition of  claim 3 , wherein the warming sensate is vanillyl butyl ether.  
     
     
         7 . The masking composition of  claim 3 , wherein the warming sensate is vanillin.  
     
     
         8 . The masking composition of  claim 4  further comprising a cooling sensate.  
     
     
         9 . The masking composition of  claim 8 , wherein the cooling sensate is selected from the group consisting of 
 (a) a compound represented by the formula:                          or salts thereof, wherein D is a straight chained or branched, unsubstituted C 1 -C 4  alkyl or alkenyl group and E is a straight chained or branched, hydroxy-substituted or unsubstituted C 1 -C 4  alkyl or alkenyl group; and    (b) a compound selected from the group consisting of menthol, menthone, camphor, pulegol, isopulegol, cineol, mint oil, peppermint oil, spearmint oil, eucalyptus oil, 3-1-menthoxypropane-1,2-diol, N-alkyl-p-menthane-3-carboxamide, 3-1-menthoxy-2-methylpropane-1,2-diol, p-menthane-3,8-diol, 2-1-menthoxyethane-1-ol, 3-1-menthoxypropane-1-ol, 4-1-menthoxybutane-1-ol, 1-(2-hydroxy-4-ethylcyclohexyl)-ethanone, menthyl 3-hydroxybutanoate, menthyl lactate, menthone glycerin ketal, 2-(2-1-menthyloxyethyl)ethanol, menthyl glyoxylate, N-methyl-2,2-isopropylmethyl-3-methylbutanamide, menthyl 2-pyrrolidone-5-carboxylate, monomenthyl succinate, alkali metal salts of monomenthyl succinate, and alkali earth metal salts of monomenthyl succinate, monomenthyl glutarate, alkali metal salts of monomenthyl glutarate, alkali earth metal salts of monomenthyl glutarate, N-[[5-methyl-2-(1-methylethyl) cyclohexyl]carbonyl]glycine, p-menthane-3-carboxylic acid glycerol ester, menthol propylene glycol carbonate; menthol ethylene glycol carbonate, and 6-isopropyl-3,9-dimethyl-1,4- dioxaspiro[4.5]decan-2-one.    
     
     
         10 . The masking composition of  claim 6 , wherein the cooling sensate is selected from menthol, 3-(1)-menthoxypropane-1,2-diol, and isopulegol.  
     
     
         11 . The masking composition of claim  claim 4  further comprising 
 (a) propylene glycol;    (b) menthol;    (c) maltol;    (d) peppermint or a peppermint fraction;    (e) (l) menthone;    (f) vanillin;    (g) a bread extract; and    (h) glycerin.    
     
     
         12 . The masking composition of  claim 4  further comprising 
 (a) vanillyl butyl ether;    (b) isopulegol;    (c) maltol;    (d) furaneol;    (e) benzyl alcohol; and    (f) triglycerides.    
     
     
         13 . A beverage comprising the masking composition of  claim 4 .  
     
     
         14 . A confection comprising the masking composition  claim 4 .  
     
     
         15 . The confection of  claim 14  in the form of a gum, tablet, chewy candy or hard candy.  
     
     
         16 . A pharmaceutical composition comprising the masking composition of  claim 4 .  
     
     
         17 . A method of masking undesirable or overly intense flavor notes of a beverage, food or orally consumable product comprising adding to the beverage, food or orally consumable product a masking composition comprising a carboxylic acid represented by the formula  
       
         
           
           
               
               
           
         
       
       wherein A is a hydrogen, C 1 -C 3  alkyl, or a salt thereof.  
     
     
         18 . A method of modulating the nerve responses in the throat and oral cavity upon ingestion of an orally consumable product comprising adding to the orally consumable product a masking composition comprising a carboxylic acid represented by the formula  
       
         
           
           
               
               
           
         
       
       wherein A is a hydrogen, C 1 -C 3  alkyl, or a salt thereof.  
     
     
         19 . The masking composition of  claim 3 , wherein the carboxylic acid is acetic acid.  
     
     
         20 . The masking composition of  claim 7 , wherein the cooling sensate is selected from methol, 3-(1)-menthoxypropane-1,2-diol and isopulegol.  
     
     
         21 . The method of  claim 17 , wherein the carboxylic acid is acetic acid.  
     
     
         22 . The method of  claim 18 , wherein the carboxylic acid is acetic acid.