US2007043215A1PendingUtilityA1

Recombinant f1-v plague vaccine

Assignee: HEATH DAVID GPriority: Aug 27, 1996Filed: Aug 27, 1996Published: Feb 22, 2007

Est. expiryAug 27, 2016(expired)· nominal 20-yr term from priority

Inventors:David G. Heath Arthur M. Friedlander George W. Anderson Susan L. Welkos

C07K 2319/00A61P 37/04A61P 31/04C07K 14/24

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Claims

Abstract

A recombinant vaccine is described which is composed of one recombinant protein comprising F1 and V antigen of Yersinia pestis. This vaccine protects experimental mice against pneumonic as well as bubonic plague produced by either F1 + or F1 − strains of Y. pestis and may provide the basis for an improved human plague vaccine.

Claims

exact text as granted — not AI-modified

1 - 30 . (canceled)  
     
     
         31 . An isolated and purified DNA fragment according to claim  1  further comprising a V antigen from other  Yersinia  species chosen from the group consisting of  Yersinia pseudotuberculosis  and  Yersinia enterocolitica.

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