US2007077252A1PendingUtilityA1

Laminin chains: diagnostic uses

58
Assignee: BIOSTRATUM INCPriority: Oct 4, 1994Filed: Sep 18, 2006Published: Apr 5, 2007
Est. expiryOct 4, 2014(expired)· nominal 20-yr term from priority
Inventors:Karl TryggvasonPekka KallunkiCharles Pyke
C07K 16/28C12Q 1/6883C07K 16/18C12Q 2600/112C12Q 2600/158C12Q 1/6886C07K 2317/76C12Q 2600/156
58
PatentIndex Score
0
Cited by
0
References
0
Claims

Abstract

The instant invention provides for the identification, diagnosis, monitoring, and treatment of invasive cells using the laminin 5 gamma-2 chain protein or nucleic acid sequence, or antibodies thereto.

Claims

exact text as granted — not AI-modified
1 . A method for intervention of γ2 chain interactions of invasive carcinogens with surrounding tissues by using anti-i2 chain antibodies to inhibit the γ2 chain biological activity of said invasive carcinogens.  
     
     
         2 . The method of  claim 1  wherein the antibody is monoclonal.  
     
     
         3 . The method of  claim 1  wherein the antibody is polyclonal.  
     
     
         4 . A method for promoting adhesion of epithelial cells by exposing said cells to intact laminin-5 molecules.  
     
     
         5 . The method of  claim 4  wherein said epithelial cells are squamous carcinoma cells.  
     
     
         6 . The method of  claim 4  wherein the epithelial cells are human keratinocytes.

Join the waitlist — get patent alerts

Track US2007077252A1 — get alerts on status changes and closely related new filings.

We store only your email — no account needed. See our privacy policy.