US2007083038A1PendingUtilityA1

Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics

Assignee: DOUCETTE-STAMM LYNNPriority: Jul 2, 1997Filed: Dec 1, 2006Published: Apr 12, 2007

Est. expiryJul 2, 2017(expired)· nominal 20-yr term from priority

Inventors:Lynn Doucette-Stamm David Bush Qiandong Zeng Timothy Opperman Chad Eric Houseweart

C07K 14/3156C07K 14/315A61K 39/092C07H 21/02A61P 31/04C07H 21/04A61K 2039/53A61K 31/7052A61K 39/00

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Claims

Abstract

The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies against the polypeptides; and methods for the production of the polypeptides. The invention also provides methods for the detection, prevention and treatment of pathological conditions resulting from bacterial infection.

Claims

exact text as granted — not AI-modified

1 . A polypeptide comprising the amino acid sequence as set forth in SEQ ID NO: 5225.  
     
     
         2 . A polypeptide having at least 99% identity to SEQ ID NO: 5225, wherein the polypeptide provides protective immunity against an infection by  S. pneumoniae.    
     
     
         3 . A polypeptide having at least 99% identity to SEQ ID NO: 5225, wherein the polypeptide elicits an immune response to an infection by  S. pneumoniae.

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