US2007110712A1PendingUtilityA1
Method of modulating fertility in animals
Individually held — no corporate assignee on recordPriority: Dec 24, 1996Filed: Jan 16, 2007Published: May 17, 2007
Est. expiryDec 24, 2016(expired)· nominal 20-yr term from priority
A61K 38/00C12N 15/8509A61K 48/00A61K 38/2093A01K 2217/05A61K 38/204C07K 14/7155A01K 2267/02A61K 38/185A01K 67/0276C07K 14/5431A01K 2217/075A01K 2227/10A01K 2227/105
49
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Claims
Abstract
The present invention relates generally to a method for controlling fertility and/or modulating the maintenance of pregnancy in animals. The present invention further provides an animal model useful for screening for therapeutic agents to treat infertility, to prevent or reduce spontaneous abortion and/or as contraceptive agents in animals.
Claims
exact text as granted — not AI-modified1 - 24 . (canceled)
25 . A method for enhancing decidualization and fertility in an animal, comprising administering to said animal an effective amount of IL-11 and IL-11Rα to agonize the interaction between IL-11 and IL-11Rα.
26 . A method for enhancing fertility in a female animal, comprising administering to said animal an effective amount of (a) IL-11 or a functional derivative thereof and (b) IL-11Rα or a functional derivative thereof, to agonize the interaction between IL-11 and IL-11Rα thereby enhancing decidualization.
27 . A method for enhancing fertility in a female animal, comprising administering to said animal an effective amount of (a) a nucleic acid molecule encoding IL-11 or a functional derivative thereof and (b) a nucleic acid molecule encoding IL-11Rα or a functional derivative thereof.Join the waitlist — get patent alerts
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