Surfactant, and an emulsion-type cosmetic composition and a liposome containing said surfactant

Abstract

The invention provides a surfactant comprising at least one trehalose-6-fatty acid ester selected from those represented by the following formula: wherein R represents a saturated or unsaturated acyl group having 8-22 carbon atoms, and may have a hydroxyl group or other substituents, and an emulsion-type cosmetic composition comprising said surfactant and a water-soluble polymer. The surfactant of the invention has excellent surface activity and safety. Also, the emulsion-type cosmetic composition has excellent long-term storage stability and sensory properties, has no irritation to skin, and gives beautiful appearance with fine surface texture. Further, the invention is a liposome having a membrane wall composed of trehalose fatty acid ester. Said liposome has excellent chemical and physical stabilities such as long-term storage stability.

1 . A surfactant comprising at least one trehalose-6-fatty acid ester represented by the following formula:  
     
       
         
         
             
             
         
       
       wherein R represents a saturated or unsaturated acyl group having 8-22 carbon atoms, and may have a hydroxy group or other substituents.  
     
   
   
       2 . A surfactant comprising at least one trehalose-6-fatty acid esters selected from the group consisting of 6-(10-undecylenyl)-trehalose, 6-lauroyl-trehalose, 6-stearoyl-trehalose, trehalose monoisostearate, trehalose monodocosanate, trehalose monolinoleate, trehalose monocaprate, and trehalose monomyristate.  
   
   
       3 . A washing agent comprising the surfactant as claimed in  claim 1 .  
   
   
       4 . The washing agent as claimed in  claim 3 , wherein the washing agent is a hair or skin washing agent.  
   
   
       5 . The washing agent as claimed in  claim 3 , wherein a content of said trehalose-6-fatty acid ester is 1-50 wt. %, preferably 10-35 wt. %.  
   
   
       6 . An emulsion-type cosmetic composition comprising at least one water-soluble polymer selected from trehalose-6-fatty acid esters represented by the following formula:  
     
       
         
         
             
             
         
       
       wherein R represents a saturated or unsaturated acyl group having 8-22 carbon atoms, and may have a hydroxyl group or other substituents.  
     
   
   
       7 . An emulsion-type cosmetic composition comprising at least one trehalose-6-fatty acid ester selected from the group consisting of 6-(10-undecylenyl)-trehalose, 6-lauroyl-trehalose, 6-stearoyl-trehalose, trehalose monoisostearate, trehalose monodocosanate, trehalose monolinoleate, trehalose monocaprate, and trehalose monomyristate, and a water-soluble polymer.  
   
   
       8 . The emulsion-type cosmetic composition as claimed in  claim 6 , wherein said water-soluble polymer is one or more of water-soluble polymers selected from the group consisting of guar gum, roastbean gum, queensseed, carageenan, galactan, arabic gum, tragacanth, pectin, mannan, starch, xanthan gum, dextrin, succinoglucan, curdlan, gelatin, casein, albumin, collagen, methyl cellulose, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, methylhydroxypropyl cellulose, soluble starch, carboxymethyl starch, methyl starch, propyleneglycol alginate, salts of alginic acid, polyvinylalcohol, polyvinylpyrrolidone, polyvinylmethylether, carboxyvinyl polymers, sodium polyacrylate, polyethyleneglycol, ethylene oxide/propylene oxide copolymers, cationated cellulose, sodium chondroitin sulfate and sodium hyaluronate.  
   
   
       9 . The emulsion-type cosmetic composition as claimed in  claim 6 , wherein a content of said trehalose-6-fatty acid ester is 0.01-20 wt. %, preferably 0.1-10 wt. % and a content of said water-soluble polymer is 0.001-40 wt. %, preferably 0.01-20 wt. %.  
   
   
       10 . The emulsion-type cosmetic composition as claimed in  claim 6 , wherein said emulsion-type cosmetic composition is a massage cream, a cleansing cream, a skin cream, a foundation cream, a makeup base, a hair cream, a massage jelly or a medicinal jelly.  
   
   
       11 . A liposome comprising a membrane wall composed of a trehalose fatty acid ester.  
   
   
       12 . The liposome as claimed in  claim 11 , wherein said trehalose fatty acid ester is trehalose difatty acid ester.  
   
   
       13 . The liposome as claimed in  claim 11 , wherein fatty acid of which said trehalose fatty acid ester is constituted is a saturated or unsaturated fatty acid which has 8-22 carbon atoms, preferably 10-18 carbon atoms, and may have a hydroxyl group or other substituents.  
   
   
       14 . A liposome comprising a membrane wall mainly composed of at least one trehalose fatty acid ester selected from the group consisting of trehalose dilaurate, trehalose dipalmitate, trehalose diundecylenate, trehalose dimyristate and trehalose distearate.