US2007166812A1PendingUtilityA1

Gamma subunit of cytokine responsive lkB-alpha kinase complex

Assignee: UNIV CALIFORNIAPriority: Aug 20, 1998Filed: Mar 9, 2007Published: Jul 19, 2007

Est. expiryAug 20, 2018(expired)· nominal 20-yr term from priority

Inventors:Michael Karin David M. Rothwarf Ebrahim Zandi

C12N 9/1205

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Claims

Abstract

The present invention provides a novel essential regulatory subunit of the IκB kinase (IKK) complex, IKK-γ. The isolated IKK-γ subunit of the invention has substantially the same amino acid sequence as SEQ ID NO: 2 shown in FIG. 2.

Claims

exact text as granted — not AI-modified

1 - 29 . (canceled)  
     
     
         30 . An isolated IκB kinase (IKK) subunit, IKK-γ, comprising the amino acid sequence SEQ ID NO: 2.  
     
     
         31 . An isolated IKK-γ fragment comprising amino acids 134-419 of SEQ ID NO:2.  
     
     
         32 . An isolated IKK-γ fragment comprising amino acids 1-300 of SEQ ID NO:2.

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