US2007179096A1PendingUtilityA1
Pharmaceutical Formulation
Est. expiryApr 24, 2016(expired)· nominal 20-yr term from priority
A61P 5/06A61K 31/4172A61K 9/19A61K 9/0019A61K 47/02A61K 47/183A61K 47/10A61P 3/04A61K 38/27A61K 47/26
49
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Claims
Abstract
The invention relates to aqueous pharmaceutical formulations comprising human growth hormone, histidine, poloxamer, phenol, and mannitol.
Claims
exact text as granted — not AI-modified1 . An aqueous pharmaceutical formulation comprising a) about 1 mg/ml to about 15 mg/ml of human growth hormone (hGH), b) histidine in an amount of about 0.05-about 0.5 mg per mg hGH, c) Poloxamer 188 in an amount of about 0.1-about 2 mg per mg hGH, d) mannitol in an isotonicity conferring amount, and e) phenol in an amount that confers a preservative effect, wherein the formulation has a pH of about 6.0-about 6.3.
2 . The formulation of claim 1 , wherein the formulation has a pH of about 6.1.Cited by (0)
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