US2007190523A1PendingUtilityA1

Method and compositions for identifying anti-hiv therapeutic compounds

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Assignee: BIRKUS GABRIELPriority: Apr 26, 2002Filed: Nov 6, 2003Published: Aug 16, 2007
Est. expiryApr 26, 2022(expired)· nominal 20-yr term from priority
Inventors:Gabriel BirkusJames M. ChenXiaowu ChenTomas CihlarEugene J. EisenbergMarcos HatadaGong-Xin HeChoung U. KimWilliam A. LeeMartin McdermottSundaramoorthi Swaminathan
C07F 9/6561A61K 31/675C07F 9/65515C07F 9/650905C40B 40/04C07F 9/650947C07F 9/6512A61K 31/66C12N 9/16C12Q 1/18A61P 31/18C07D 491/04C07D 243/04C12Q 1/44C12Q 1/37C07F 9/6506C07D 213/75C07D 401/06C07D 239/49C07F 9/58C07F 9/4006C07F 9/65583C07D 403/06C07F 9/65335C07D 265/18C07D 231/20C07D 213/85C07F 9/65128C07D 471/14C07D 239/80C07D 307/68G01N 2500/04G01N 33/5038C07D 233/42G01N 2333/16A61P 43/00C07F 9/645C07D 231/12A61K 31/4155C07F 9/38C07F 9/40
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Claims

Abstract

The invention relates to methods and compositions for identifying compounds having therapeutic activity against human immunodeficiency virus (HIV).

Claims

exact text as granted — not AI-modified
1 . A method comprising 
 (a) identifying a non-nucleotide prototype compound;    (b) substituting the prototype compound with a phosphonate-containing group to produce a candidate compound; and    (c) determining the anti-HIV activity of the candidate compound.    
   
   
       2 - 250 . (canceled)

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